Where mTOR research is happening

Annual meeting of the Gerontological Society of America (GSA) – the largest interdisciplinary US society for research on aging. Theme: 'Reinforcing Resilience in Aging Science, Research and Education.'

Why it matters hereGSA is the oldest and largest interdisciplinary US organization devoted to research on aging; its program regularly includes translational geroscience and longevity sessions (the 2026 late-breaking abstract track explicitly names 'translational geroscience and longevity' as a theme), drawing mTOR/rapamycin-adjacent aging biology researchers alongside clinical and social gerontology. mTOR is not itself a named track, but geroscience/aging-biology is a major recurring theme. Broader in scope than a topical mTOR meeting.

Venue

Gaylord National Resort & Convention Center

Organisers

Gerontological Society of America (society-organized; no named individual chairs published yet)

Link

Conference site →

Calendar

Add to Google Calendar Apple / Outlook (.ics)

NIA-hosted summit (with the NIH Geroscience Interest Group) bringing together academic and industry researchers, clinicians, and other stakeholders in geroscience across 8 sessions to assess the state of the science, identify gaps, and build a 3-5 year research roadmap focused on healthspan.

Why it matters hereNIH/NIA's flagship cross-institute geroscience summit. Gerotherapeutic development, hallmarks-of-aging biology, and healthspan biomarker sessions directly track the Atlas's nutrient-sensing/mTOR-aging axis; Session V (Gerotherapeutics for Health, Clinical Trials) and Session VII (New Initiatives in Geroscience) are the most mTOR/rapamycin-adjacent.

Venue

NIH Main Campus, Building 35

Organisers

NIH/NIA Geroscience Interest Group (GSIG). Welcome: Jay Bhattacharya (NIH Director), Richard Hodes (NIA Director). Session chairs: Juan Carlos Izpisua Belmonte, Jesse Poganik, Eileen Crimmins, John Beard, John Newman, Siobhan Malany, Jodi Nunnari, Elizabeth Necka. Overall moderators: Felipe Sierra, Vadim Gladyshev, Tony Wyss-Coray.

Speakers

Keynote: Luigi Ferrucci. Session I: Juan Carlos Izpisua Belmonte, Thomas Rando, George Kuchel, Guanghui Liu. Session II: Jesse Poganik, Yousin Suh, Paola Sebastiani. Session III: Eileen Crimmins, Cathal McCrory, Jessica Faul, Dana Goldman, Andrew Scott. Session IV: Daniel Belsky, Jennifer Brach, Su-In Lee, Michael Snyder. Session V: John Newman, Heinrich Jasper, James Peyer, Brianna Stubbs. Session VI: Warren Casey, Kristen Brennand, Joseph Wu, Luiz Eduardo Bertassoni, Francesca Duncan. Session VII: Jamie Justice, Joan Mannick, Andrew Brack. Session VIII: TBD. Roundtable participant: Steven Austad.

In the Atlas

Joan B. Mannick

Link

Conference site →

Calendar

Add to Google Calendar Apple / Outlook (.ics)

Biennial-ish meeting of the Sociedad Española de Autofagia (SEFAGIA, Spanish Society of Autophagy), gathering autophagy and related-field researchers for several days of cutting-edge science, collaboration, and networking. Prior editions (SEFAGIA 2024, 2025) featured keynotes such as Robbie Loewith, Marja Jäättelä, and Terje Johansen.

Why it matters hereConfirmed keynotes Ana Maria Cuervo (Albert Einstein College of Medicine – chaperone-mediated autophagy and lysosomal-mTORC1 crosstalk pioneer), Ivan Đikić (Goethe University Frankfurt – ubiquitin-autophagy signaling), and Nektarios Tavernarakis (University of Crete – autophagy and aging, C. elegans). Direct mechanistic overlap with the Atlas's mTORC1-lysosome-autophagy axis.

Organisers

Sociedad Española de Autofagia (SEFAGIA); named organizing/scientific committee for the 2027 edition not yet publicly posted.

Speakers

Ana Maria Cuervo, Ivan Đikić, Nektarios Tavernarakis (confirmed international keynotes; full speaker roster not yet public)

In the Atlas

Ana Maria CuervoNektarios Tavernarakis

Link

Conference site →

Calendar

Add to Google Calendar Apple / Outlook (.ics)

Keystone Symposium (joint with 'Induced Proximity and Targeted Protein Degradation') covering core autophagy machinery, selective autophagy, non-canonical autophagy pathways, and therapeutic exploitation of autophagy including AUTACs.

Why it matters heremTORC1 is the principal negative regulator of autophagy initiation; sessions on lysosomal integration of biosynthetic/catabolic signaling (Zoncu) and autophagy in aging (Boya, Simon) are directly relevant to the Atlas's mTOR-autophagy-aging axis.

Venue

Fairmont Banff Springs

Organisers

Scientific Organizers: Hong Zhang, Susan Ferro-Novick, Hitoshi Nakatogawa.

Speakers

Keynote: Noboru Mizushima. Invited: Hitoshi Nakatogawa, Sascha Martens, Nobuo N. Noda, Susan Ferro-Novick, Florian Wilfling, Eric H. Baehrecke, Ana Maria Cuervo, Hong Zhang, Xiaochen Wang, Roberto Zoncu, Vojo Deretic, Yan Zhao, Mondira Kundu, Dimitri Krainc, Patricia Boya, Ai Yamamoto, Anna Katharina Simon, Boxun Lu, Vassiliki Nikoletopoulou.

In the Atlas

Roberto ZoncuNoboru MizushimaMondira KunduAna Maria CuervoVojo Deretic

Link

Conference site →

Calendar

Add to Google Calendar Apple / Outlook (.ics)

Keystone Symposium, presented in partnership with the Ludwig Institute for Cancer Research (Princeton Branch), on interactions between tumor and host metabolism: how environmental and whole-body changes, diet, and aging affect tumor growth and progression.

Why it matters hereSuccessor to the Atlas's existing 'Tumor Metabolism' Keystone entry (2026). Direct mTORC1 relevance via Andrea Ballabio's confirmed talk 'Paracrine Activation of mTORC1 in the Tumor Microenvironment'; a dedicated Day-3 session ('Frontiers in Stress Responses and Aging in Cancer') covers aging-cancer metabolic crosstalk. Co-organized by Marcia Haigis (Co-Director, Paul F. Glenn Center for the Biology of Aging at Harvard) and Lydia Lynch (Princeton/Ludwig).

Venue

Ludwig Institute Princeton University

Organisers

Scientific Organizers: Marcia C. Haigis (Harvard Medical School); Lydia Lynch (Princeton University).

Speakers

Keynote: Karen H. Vousden (Francis Crick Institute). Confirmed speakers: Semir Beyaz (CSHL), Ruaidhri P. Jackson (Harvard Medical School), Michael Skinnider (Princeton), Garry P. Nolan (Stanford), Joshua D. Rabinowitz (Princeton), Stacey D. Finley (USC), Hongbo Chi (St. Jude), Leeat Keren (Weizmann Institute), Andrea Ballabio (Telethon Institute of Genetics and Medicine), Luke A. J. O'Neill (Trinity Biomedical Sciences Institute), Lydia Lynch (Princeton), Alison Ringel (MIT), Marcia C. Haigis (Harvard), Ashani T. Weeraratna (Johns Hopkins), Sarah-Maria Fendt (VIB-KU Leuven), Noga Ron-Harel (Technion), Jonathan D. Powell (Calico Life Sciences), Ping-Chih Ho (Ludwig Institute), Carl H. June (UPenn).

In the Atlas

Hongbo ChiAndrea BallabioJonathan D. Powell

Link

Conference site →

Calendar

Add to Google Calendar Apple / Outlook (.ics)

Keystone Symposia conference on integrative mitochondrial medicine, spanning mitochondrial genome editing, synthetic biology, imaging, precision medicine for mitochondrial disease, and mitochondrial transplantation.

Why it matters hereMitochondrial quality control, biogenesis and dynamics are tightly coupled to mTOR/AMPK nutrient-sensing signaling (mitophagy, PGC-1alpha-driven biogenesis); direct companion event to the Atlas's existing 'Mitochondria Signaling in Physiology and Disease' Keystone meeting. Same basis as that entry: mTOR is not a named program topic, the connection is inferred mechanistic adjacency. Retained for completeness, not prioritised.

Venue

Fairmont Banff Springs

Organisers

Nils-Goran Larsson (Karolinska Institutet); Aleksandra Filipovska (University of Western Australia)

Speakers

Vamsi K. Mootha; Wendy Shoop; Min Jiang; Carlos T Moraes; Oliver Rackham; Martin Fussenegger; Aleksandra Filipovska; Danielle Grotjahn; Antentor O Hinton Jr.; Gulcin Pekkurnaz; Elisa Motori; Claes Gustafsson; Thomas Keating; Michio Hirano; Christian Frezza; Nils-Goran Larsson; Natalie Niemi; Jared Rutter; Robert McFarland; Janine Santos; Heidi M. McBride

In the Atlas

Vamsi K. Mootha

Link

Conference site →

Calendar

Add to Google Calendar Apple / Outlook (.ics)

One-day in-person meeting of the New York Academy of Sciences Cancer and Signaling Discussion Group, on how tumour cells exploit signalling and metabolic pathways in the tumour microenvironment to drive malignant growth. Recurring annual format; the 2026 edition ran 24 Mar 2026 and is closed.

Why it matters hereA cancer-metabolism meeting rather than an mTOR meeting: PI3K-AKT-mTOR signalling is standard content in this field but is not named in the announced scope, and no programme is published yet for 2027. Listed as a low-cost, single-day venue in the same subject area as several Atlas authors work in, not as a source of mTOR-specific primary data.

Organisers

New York Academy of Sciences, Cancer and Signaling Discussion Group; lead supporter Pfizer (the 2026 edition was co-presented with NYU Langone Health)

Speakers

Checked 13 Sep 2026: registration open, but speakers, chairs, fees and any abstract deadline are not yet published for 2027; the events.nyas.org speaker sub-pages now return 404. Surfaced because Brendan Manning and Christian Dibble both referenced the 2026 edition on Bluesky — neither is named on any official page, so treat their involvement as unconfirmed.

Link

Conference site →

Calendar

Add to Google Calendar Apple / Outlook (.ics)

The largest cancer research meeting in the world, spanning basic, translational and clinical oncology.

Why it matters hereThe principal venue where human data on mTOR-pathway inhibitors surface first. Rapalog resistance mechanisms, PI3K-AKT-mTOR biomarker work, and the clinical development of third-generation mTOR inhibitors are all reported here. Added to correct a structural bias in this table: the mTOR evidence base is heavily basic-science and geroscience, while the human evidence that the Atlas's translation-gap thesis depends on is adjudicated in oncology.

Venue

Orange County Convention Center

Organisers

American Association for Cancer Research (AACR)

Speakers

Program not yet published; Linked_Authors left blank until speakers are confirmed.

Link

Conference site →

Calendar

Add to Google Calendar Apple / Outlook (.ics)

Keystone Symposia conference examining emerging strategies for promoting healthy aging, with a focus on biomarkers of aging, therapeutic development, and interventions to improve quality of life. Sessions cover geromedicine, biomarkers of aging, non-pharmacologic approaches, combination therapies, drug target identification, and translational/regulatory challenges.

Why it matters hereCo-organized by Brian K. Kennedy, a leading rapamycin/mTOR and NAD+ longevity researcher; geromedicine and combination-therapy sessions are directly adjacent to the Atlas's mTOR-intervention focus.

Venue

NTUH International Convention Center

Organisers

Scientific Organizers: Derek Huffman (Albert Einstein College of Medicine); Kristen Fortney (BioAge Labs); Brian K. Kennedy (National University of Singapore); Shu-Chun Teng (National Taiwan University).

Speakers

Programme published by Oct 2026. Keynote: Nir Barzilai (Albert Einstein College of Medicine). Session speakers include Joan Mannick (Altos Labs), who has three studies in the Atlas and appears in 'New Breakthroughs and Clinical ‘Wins’ in Aging Therapeutics'; also P. Eline Slagboom, Yousin Suh, Daniel Belsky, John Newman, Heike Bischoff-Ferrari, Andrea Maier, Sara Espinoza, Rafael de Cabo, Nathan K. LeBrasseur and Adam Konopka.

In the Atlas

Brian K. KennedyJoan B. Mannick

Link

Conference site →

Calendar

Add to Google Calendar Apple / Outlook (.ics)

Long-running (6th edition, since 2015) small-format geroscience conference on molecular/cellular mechanisms of aging and translation into human interventions – exercise, chronobiology, tissue-specific aging biomarkers, genetic variation, and systems biology approaches to healthy aging.

Why it matters hereCore geroscience meeting chaired by leading nutrient-sensing/aging researchers (Linda Partridge, Heinrich Jasper, William Mair – all with major contributions to TOR/insulin-IGF1 longevity pathway work); sessions on pharmacological and lifestyle interventions targeting core aging mechanisms directly overlap the Atlas's mTOR/geroscience scope. Rapamycin/mTOR inhibition is a recurring theme in aging-intervention pharmacology alongside adjacent biology, as at ARDD.

Venue

Meliá Durrës

Organisers

Linda Partridge (UCL); Heinrich Jasper (Genentech); William Mair (Harvard)

Speakers

Rafael de Cabo; Leanne Jones; Andrea Maier; Tony Wyss-Coray; Salvador Aznar-Benitah; Heike Bischoff-Ferrari; Ed Chouchani; Luigi Ferrucci; Chiara Herzog; Mika Kivimaki; Nathan LaBrasseur; Courtney Peterson; Daniel Promislow; Nicholas Stroustrup; Dario Valenzano

In the Atlas

Linda Partridge

Link

Conference site →

Calendar

Add to Google Calendar Apple / Outlook (.ics)

GRC on Lysosomal Diseases, themed "Understanding Lysosomes to Enable Innovative Therapies". Five-day closed meeting on unpublished work spanning fundamental lysosomal biology and therapy development for lysosomal storage disorders. Preceded by the associated Gordon Research Seminar (15-16 May 2027). Application deadline 18 April 2027.

Why it matters hereIndirect but real: the lysosomal surface is the platform on which mTORC1 is activated (Rag GTPases, Ragulator/LAMTOR, v-ATPase), and mTORC1 in turn controls the TFEB/TFE3 lysosomal-biogenesis program. Lysosomal-storage-disease biology and mTORC1-TFEB signalling are studied by overlapping groups (e.g. Ballabio, Zoncu, Ferguson, Settembre). Scope note: this is a lysosome-biology meeting, not an mTOR-centred one – mTOR content will be a subset of the program. Tier is provisional: the programme is unpublished as of 2026-08-15 (due 19 August 2026), so relevance is currently inferred from the community rather than from stated sessions; revisit for a possible TIER 2 once sessions are announced.

Venue

Les Diablerets Conference Center / Eurotel Victoria

Organisers

Chairs and vice-chairs not yet published by GRC as of 2026-08-15; preliminary program with invited speakers due 19 August 2026.

Speakers

Not yet announced — GRC publishes the speaker list with the preliminary program (expected 19 August 2026).

Link

Conference site →

Calendar

Add to Google Calendar Apple / Outlook (.ics)

The eighth Cold Spring Harbor Laboratory meeting on Mechanisms of Metabolic Signaling & Disease, bringing together researchers spanning biochemistry, molecular biology, physiology, and pathophysiology to define the role and regulation of metabolic signals across pathways, cell types, and disease states.

Why it matters hereCore CSHL metabolic-signaling meeting with dedicated sessions on 'Metabolic Signaling' and 'Metabolism, Growth, and Proliferation' – directly overlapping mTOR/nutrient-sensing biology; comparable in scope to the already-curated CSHL: Mechanisms of Aging meeting. mTOR is a major recurring theme alongside adjacent metabolic signalling, rather than a named headline subject.

Venue

Cold Spring Harbor Laboratory

Organisers

Bart Deplancke (EPFL, Switzerland); Sarah-Maria Fendt (VIB Leuven, Belgium); Deborah Muoio (Duke University School of Medicine)

Link

Conference site →

Calendar

Add to Google Calendar Apple / Outlook (.ics)

Fusion Conferences residential meeting on the regulation of protein synthesis from single molecules to whole organisms, with emphasis on ribosome heterogeneity and translational rewiring in cancer. Appears to be the inaugural edition; no edition number is printed.

Why it matters hereThe best-characterised output of mTORC1 is cap-dependent translation, through phosphorylation of 4E-BP1 and S6K1, and this meeting is where that branch of the pathway is treated as its own field rather than as a downstream readout. Chaired in part by Davide Ruggero, who has three studies in the Atlas, and sitting in the Sonenberg lineage of translational control. Relevant to the question of which mTORC1 substrates are rapamycin-resistant, which is exactly where rapamycin and bi-steric inhibitors diverge.

Venue

Meliá Durrës

Organisers

Chairs: Maria Barna (Stanford), Davide Ruggero (UCSF), Poul Sorensen (UBC), Anne Willis (Cambridge)

Speakers

16 invited speakers. Deadlines as published on 13 Sep 2026: early-bird registration and talk/abstract submission 19 Nov 2026; poster submission and registration/payment 18 Feb 2027. Fees include three nights' accommodation and meals: student EUR 1,206; shared room EUR 2,190 early / EUR 2,286 full; single EUR 2,516 / EUR 2,611. Surfaced via Ruggero Lab and Bar-Peled on Bluesky (#TCCO).

In the Atlas

Davide Ruggero

Link

Conference site →

Calendar

Add to Google Calendar Apple / Outlook (.ics)

Second edition of the Fusion Conferences meeting on redox control (ROS, NAD, glutathione) in cellular health, cancer, ageing, neurodegeneration and cardiometabolic disease. The first edition ran 3-6 Nov 2025 in Tulum, Mexico.

Why it matters hereRelevance comes from the attendee list, not from the programme, which is exactly what tier 3 is for. The announced theme is redox control (ROS, NAD, glutathione, ferroptosis) and mTOR is nowhere in it. What makes this meeting matter to the Atlas is that the published invited-speaker list contains both Brendan D. Manning and David M. Sabatini, the two most heavily represented authors in the corpus (10 and 46 studies), alongside Eileen White and Matthew Vander Heiden. That is the strongest author overlap of any meeting in this table. The mechanistic link that does exist runs through oxidative regulation of the TSC complex and the shared metabolite pool supporting anabolism, but it is inference, not billed content.

Venue

Meliá Durrës

Organisers

Chairs: Navdeep Chandel, Celeste Simon, Karen Vousden. Plenary lecture: William Kaelin (Harvard)

Speakers

20 invited speakers, including Brendan Manning, David Sabatini, Kivanç Birsoy, Ralph DeBerardinis, Marcus Conrad, Erika Pearce, Matthew Vander Heiden and Eileen White. Deadlines as published on 13 Sep 2026: early bird and talk submission 24 Nov 2026; poster submission and registration/payment 23 Feb 2027. Fees include three nights' accommodation and meals: student EUR 1,206; shared room EUR 2,190 early / EUR 2,286 full; single EUR 2,516 / EUR 2,611. Surfaced via Bar-Peled and Manning on Bluesky (#RedoxBio25 referred to the 2025 first edition).

In the Atlas

Brendan D. ManningDavid M. Sabatini

Link

Conference site →

Calendar

Add to Google Calendar Apple / Outlook (.ics)

The largest clinical oncology meeting worldwide; where practice-changing trial results are first presented.

Why it matters hereWhere mTOR inhibition meets clinical endpoints in humans. The everolimus registration trials (RECORD-1 in renal cell carcinoma, BOLERO-2 in breast cancer, RADIANT-3 in neuroendocrine tumours - Motzer RJ, Baselga J, Yao JC, all Atlas authors) were reported at ASCO, as were the RMC-5552 combination findings. The purest expression of the Atlas's translation-gap axis: mTOR inhibitors that work in mice tested against hard human endpoints.

Venue

McCormick Place Convention Center

Organisers

American Society of Clinical Oncology (ASCO)

Speakers

Program not yet published; Linked_Authors left blank until speakers are confirmed.

Link

Conference site →

Calendar

Add to Google Calendar Apple / Outlook (.ics)

Joint annual meeting of the American Society of Transplantation (AST) and the American Society of Transplant Surgeons (ASTS); >4,000 attendees. (ATC 2026, Boston, 20-24 June 2026, has already passed.)

Why it matters hereTransplantation is the largest human exposure dataset in existence for sirolimus and everolimus (approved for rejection prophylaxis long before any geroscience trial) and the origin of the canonical adverse-effect profile the Atlas records: hyperlipidaemia, insulin resistance and new-onset diabetes, impaired wound healing, mucositis, infection. Supplies the human safety denominator that geroscience trials cite second-hand. Atlas authors in this space: Budde K, Saemann MD, Singer LG.

Venue

Washington State Convention Center

Organisers

American Society of Transplantation (AST) and American Society of Transplant Surgeons (ASTS)

Speakers

Program not yet published; Linked_Authors left blank until speakers are confirmed.

Link

Conference site →

Calendar

Add to Google Calendar Apple / Outlook (.ics)

Long-running (since 1962) flagship Gordon Research Conference on the biology of aging, held biennially, alternating US/Europe venues. Brings together the core international aging-biology research community across molecular, cellular, and organismal scales.

Why it matters heremTOR/nutrient-sensing signaling (rapamycin, TOR pathway, autophagy) has been a recurring major session theme at prior editions of this conference given its central role in aging biology; a flagship venue for mTOR-and-aging primary research even when not named in the title.

Venue

Renaissance Tuscany Il Ciocco

Organisers

Chairs: Peter Sudmant; Eva R. Hoffmann. Vice Chairs: Ashley E. Webb; Jennifer Regan.

Speakers

Preliminary programme (released October 2026) speakers and discussion leaders: Vera Gorbunova; Juan Vazquez; Ingrid Fetter-Pruneda; Dario Riccardo Valenzano; Serena Nik-Zainal; Melike Donertas; Christian Gonzalez-Billault; Zhengming Chen; Luigi Ferrucci; Alessandro Ori; Miranda Orr; Anne Schaefer; Bjoern Schwer; Andrew Dillin; David Glass; Richard Miller; Bjorn Schumacher; Alex Cagan; Anne Brunet; Francesca Duncan; Pankaj Kapahi; Jennifer Regan; Christina Camell; Kosuke Hashimoto; Darragh Duffy; Andreas Pfenning; Claire Bedbrook.

In the Atlas

Richard A. MillerPankaj Kapahi

Link

Conference site →

Calendar

Add to Google Calendar Apple / Outlook (.ics)

2027 FASEB Science Research Conference on nutrient sensing and metabolic signalling: how cells and whole organisms adapt to changing nutrient states, and how defects in those mechanisms underlie metabolic disease. The meeting is pitched at the level of insulin-responsive metabolic tissues and integrated physiology, with obesity, diabetes, MASLD, cardiovascular disease, skeletal muscle atrophy, cancer and aging named as the clinical areas covered. Co-located with The Molecular Metabolism Conference: From Cell Biology to Systems Physiology, and includes Meet the Experts dine-around sessions and career-development sessions for early-career scientists.

Why it matters hereNutrient sensing and metabolic signalling are the named subject of the whole conference, not a neighbouring theme. Brendan D. Manning (Harvard), one of the five researchers the Atlas tracks most closely and the author of 11 studies in the corpus, is one of the two conference organizers; the organizing role is listed on the FASEB conference page. No invited-speaker list had been published as of 9 Oct 2026, so the mTOR content of individual sessions cannot yet be read off the programme.

Venue

The Galt House Hotel

Organisers

Anna Thalacker-Mercer (University of Alabama at Birmingham); Brendan D. Manning (Harvard University)

Speakers

No invited speakers published as of 9 Oct 2026; registration opens November 2026. Early registration and early abstract deadline 14 Jun 2027, regular registration deadline 2 Aug 2027.

In the Atlas

Brendan D. Manning

Link

Conference site →

Calendar

Add to Google Calendar Apple / Outlook (.ics)

Small, drug-development-focused conference jointly organised by AACR, the NCI and the EORTC; the main venue where first-in-human data on novel targeted agents are reported before journal publication.

Why it matters hereDirect provenance for the Atlas's own Schram 2025 entry: the first-in-human phase 1/1b data for RMC-5552, the first bi-steric mTORC1-selective inhibitor in the clinic, were presented here (Abstract C020, 2023) before the Clinical Cancer Research paper. This is where Open Question 2 (inhibit mTORC1 without affecting mTORC2) is being answered in humans rather than in mice: bi-steric selectivity relieves the mTORC2-mediated hyperglycaemia that limited earlier pan-mTOR inhibitors. Also the venue for 4E-BP1 pharmacodynamics and mucositis management.

Venue

Sheraton Grand Chicago Riverwalk

Organisers

AACR, NCI, EORTC

Speakers

2027 program not yet published; Linked_Authors left blank until speakers are confirmed.

Link

Conference site →

Calendar

Add to Google Calendar Apple / Outlook (.ics)

FASEB Science Research Conference on chromatin and epigenetic change as a driver of ageing and age-related disease. Small residential format (invited talks plus poster-only submitted abstracts), held at a single hotel venue over four days.

Why it matters heremTOR does not appear in the title or in the published programme, and the connection is indirect: epigenetic drift is a separate hallmark of ageing from nutrient sensing, and the two are linked mainly through metabolite availability for chromatin-modifying enzymes (acetyl-CoA, SAM, alpha-ketoglutarate). Listed because this is where the ageing-epigenetics community meets and because that metabolite link is the plausible interface with mTORC1-driven anabolism, not because any mTOR content is advertised.

Venue

The Grand Hotel Malahide

Organisers

Ashley Webb (Buck Institute, lead), Ashby Morrison (Stanford), Berenice A. Benayoun (USC), Ernesto Guccione (Icahn School of Medicine at Mount Sinai)

Speakers

Keynotes: Dena Dubal (UCSF), Yang Shi (Ludwig Institute, Oxford). Deadlines as published on 13 Sep 2026: extended poster-abstract submission 14 Sep 2026, early registration 7 Sep 2026 (passed), housing 28 Sep 2026, regular registration 12 Oct 2026. Fees not published on the summary page. Surfaced via Brunet Lab on Bluesky, who posted it as "the FASEB on Epigenetics and Aging" — that is not the official title and Anne Brunet is not listed as an organiser or keynote.

Link

Conference site →

Inaugural conference of the newly founded European Federation for Aging Research (EFAR), which unites the German (DGfA), Dutch (DUSRA), Nordic, and British (BSRA) national aging-research societies to foster cross-European collaboration, funding coordination, and knowledge exchange in aging biology.

Why it matters hereGeneral aging-biology conference (cellular senescence, DNA repair, healthspan, geroscience) featuring Linda Partridge, a leading dietary-restriction/longevity signaling researcher already represented in the Atlas corpus, plus other senior aging-mechanism researchers. mTOR is not a named subject of the programme; relevance is inferred from who attends.

Venue

MPI for Biology of Ageing & CECAD Research Center

Organisers

Björn Schumacher (chair, Cologne); David Vilchez (Cologne); Anne Schaefer (Cologne); Morten Scheibye-Knudsen (Denmark); Lene Rasmussen (Denmark); Folkert Kuipers (Netherlands); Joris Deelen (Netherlands); Riekelt Houtkooper (Netherlands); David Weinkove (UK); Hartmut Geiger (Germany); Helen Morrison (Germany); Ira Milosevic (Portugal/UK)

Speakers

George Garinis; Laura Niederhofer; Linda Partridge; Luca Scorrano; Uri Alon; Sara Hägg; Lumír Krejčí; Nathan LeBrasseur; Elsa Longarinho; Matthias Mann; Eija Pirinen; Eline Slagboom; Guido Kroemer; Wojciech Pokrzywa; Emma Teeling

In the Atlas

Linda PartridgeLuca ScorranoGuido Kroemer

Link

Conference site →

Annual meeting of the French Association for Autophagy Research (CFATG), featuring invited international keynote speakers and abstract-selected talks and posters. Abstract and early-bird registration deadline: July 31, 2026.

Why it matters hereFeatures keynote Roberto Zoncu (UC Berkeley – leading mTOR/lysosome researcher and mTOR-autophagy axis expert), Sharon Tooze (Crick Institute, autophagy initiation upstream of mTOR), and Ian Ganley (mitophagy). Direct mechanistic overlap with Atlas autophagy-mTOR studies.

Venue

FIAP Jean Monnet, 14th arrondissement

Organisers

CFATG Organizing Committee: Guillaume Beauclair, Aurore Claude-Taupin, Audrey Esclatine, Pierre-Emmanuel Joubert, Delphine Judith, Mojgan Djavaheri-Mergny, Etienne Morel. (Updated from official site; corrects earlier abbreviated organizer list.)

Speakers

Ian Ganley, Carine Joffre, Louis Lapierre, Katja Simon, Sharon Tooze, Roberto Zoncu

In the Atlas

Ian G. GanleyRoberto Zoncu

Link

Conference site →

Fourth edition of the Fusion Conferences residential meeting on metabolism in aging, physiology and disease. Sessions cover developmental and stem cell metabolism, aging metabolism, systemic metabolism in health and disease, organellar metabolism, metabolic drug discovery and dietary interventions, technology development, computational and AI-based approaches, and metabolites as signalling molecules.

Why it matters heremTOR is not billed anywhere in the programme, which is organised around mitochondria, lipids, metabolites and metabolic proteomics. The relevance comes from the speaker list rather than from the announced content: Brian K. Kennedy, who has three studies in the Atlas, speaks on 'Maximising healthspan – interventions and clocks', and Christina Towers on leveraging autophagy in pancreatic cancer. The 'aging metabolism' and 'metabolic drug discovery and dietary interventions' sessions sit next to the nutrient-sensing question without naming it.

Venue

Dolce CampoReal Lisboa

Organisers

Chairs: Anna Krook (Karolinska Institute); Christian Metallo (Salk Institute); Peter J. Mullen (University of Southern California)

Speakers

19 confirmed invited speakers, including Brian Kennedy (National University of Singapore), Navdeep S. Chandel, Karen Vousden, Lydia Lynch, Christina Towers, Ed Chouchani, Heather Christofk, Mark Febbraio and Anu Suomalainen Wartiovaara. Early-bird, talk, poster and registration deadlines had all closed as of 7 Oct 2026.

In the Atlas

Brian K. Kennedy

Link

Conference site →

Annual conference from the Biomarkers of Aging Consortium convening geroscience researchers to advance standardized, clinically validated biomarkers of aging and assess longevity intervention outcomes.

Why it matters hereBroad geroscience/biomarkers meeting; several speakers (Gladyshev, Verdin, Rando, Gorbunova, Horvath) work on nutrient-sensing and metabolic longevity pathways adjacent to the Atlas's mTOR-aging axis, though the program itself is not mTOR-specific. Downgraded to Tier 3: relevance rests on speaker affiliation rather than program content – no mTOR session, no mTOR-titled talk. Retained for completeness, not prioritised.

Venue

Joseph B. Martin Conference Center, Harvard Medical School

Organisers

Conference Chairs: Vadim Gladyshev, Mahdi Moqri, Chiara Herzog, Andrea Cipriano, Jesse Poganik.

Speakers

Omar Abudayyeh, Maxim Artyomov, Dan Belsky, Heike Bischoff-Ferrari, Martin Borch Jensen, Ed Boyden, Peter Fedichev, Jennifer Garrison, Vadim Gladyshev, Vera Gorbunova, Clare Gustafson, Steve Horvath, Michael Levin, João Pedro de Magalhães, Samantha Morris, Thomas Rando, Birgit Schilling, Vittorio Sebastiano, Mike Snyder, Eric Verdin.

Link

Conference site →

Cell Press Symposium exploring the cellular and molecular hallmarks of aging – from metabolism and disease to gerotechnology and gerotherapeutics.

Why it matters hereDeregulated nutrient sensing (mTOR, AMPK, IIS) is a canonical hallmark of aging; organizers include caloric-restriction (de Cabo) and autophagy (Cuervo) leaders whose work overlaps mTOR biology.

Venue

Melia Sevilla Hotel

Organisers

Organizers: Rafael de Cabo (NIA); Ana Maria Cuervo (Albert Einstein); Cell Press editors Mari-Carmen Fernandez-Aguera (Cell Metabolism), Novella Guidi (Cell Reports), Amber Mueller (Cell). Keynote: Luigi Ferrucci (NIA). (Updated 2026-07-26: named Cell Press editors now published, previously generic.)

Speakers

Keynote Luigi Ferrucci; confirmed speakers include Berenice Benayoun, Haim Cohen, Dolores Corella, Clara Correia-Melo, Vishwa Deep Dixit, David Glass, Mari-Carmen Gomez-Cabrera, among others.

In the Atlas

Ana Maria Cuervo

Link

Conference site →

The 13th Aging Research & Drug Discovery (ARDD) meeting -- flagship translational geroscience conference now organized by Insilico Medicine, relocated for 2026 to Harvard University. Tracks: Clinical Development/Longevity Medicine (Oct 1), AI in Drug Discovery (Oct 2), Future Technology (Oct 3).

Why it matters hereAs with prior editions, rapamycin/mTOR-based interventions are a core geroscience topic; a key future venue to track for mTOR translational work.

Venue

David Rubenstein Treehouse, Harvard University

Organisers

Organized by Insilico Medicine. Chairs: Vadim Gladyshev (Executive Chair, Harvard Medical School); Jesse Poganik (Co-Chair, Harvard Medical School); Alex Zhavoronkov (Co-Chair, Insilico Medicine); Morten Scheibye-Knudsen (Co-Chair, Univ. of Copenhagen); Daniela Bakula (Co-Chair, Univ. of Copenhagen); Evelyne Bischof (Longevity Medicine Co-Chair, Sheba Longevity Center); Maximilian Unfried (AI in Drug Discovery Track Co-Chair, National Univ. of Singapore). Tier 1 sponsors include Eli Lilly.

Speakers

More speakers to be announced as of July 2026 (per official site).

Link

Conference site →

First dedicated international scientific conference on aging and healthspan in animals (canine-focused, animal-wide scope). Eight tracks: canine longevity, comparative biology of aging, model/non-model organisms, biomarkers/aging clocks, longevity interventions, veterinary geroscience, cross-species translation, early-career research.

Why it matters hereCross-species geroscience forum featuring leading mTOR/aging researchers (e.g. Matt Kaeberlein of the Dog Aging Project); companion-animal aging interventions are directly relevant to mTOR/rapamycin translational research (rapamycin dog aging trials). Not the sole subject of the meeting, but a named, substantive intervention class under discussion, not just inferred mechanistic adjacency.

Organisers

Vyom Goel (Founder, Animal Longevity Summit)

Speakers

Matt Kaeberlein (Dog Aging Project); Vera Gorbunova (University of Rochester); Aubrey de Grey (LEV Foundation); Varun Dwaraka (TruDiagnostic); Liz Parrish (BioViva); Raghav Sehgal (Yale) — additional speakers to be announced

In the Atlas

Matt Kaeberlein

Link

Conference site →

Triennial European meeting on AMPK and nutrient-sensing signalling. Published program includes dedicated sessions 'Beyond AMPK: nutrient-sensing pathways in health and diseases', 'AMPK family in cancer, aging and longevity', and 'AMPK and nutrient sensors in organelle biology'.

Why it matters hereAMPK is the principal upstream antagonist of mTORC1: it inhibits mTORC1 both directly (Raptor Ser792) and via TSC2, the exact wiring already in the Atlas corpus (Shaw / Inoki / Gwinn). The program's explicit 'Beyond AMPK: nutrient-sensing pathways' and 'AMPK family in cancer, aging and longevity' sessions cover mTOR as the reciprocal arm of energy sensing. UPDATE (2026-07-22): official speaker list is now published and does NOT include Hardie or Shaw as previously speculated; confirmed speakers instead include Atlas authors Hongbo Chi (immunometabolism/AMPK-mTOR crosstalk in T cells) and Thomas Weichhart (mTOR/immunometabolism), both re-linked below in place of Shaw RJ.

Organisers

European AMPK community (organised via atoutcom.com/ampk); linked to EU-METAHEART COST Action CA22169

Speakers

Official speaker list published (atoutcom.com/ampk/speakers, as of 2026-07-20). Keynote speakers: Hongbo Chi (St. Jude Children's Research Hospital, USA), Kei Sakamoto (Novo Nordisk Foundation Center for Basic Metabolic Research, Copenhagen, Denmark). Invited speakers: Elena Baena-Gonzalez (Oxford), Olga Barca-Mayo (Santiago de Compostela), Julien Courchet (Univ. Claude Bernard Lyon 1), Bart Everts (Leiden UMC), Madelon Maurice (UMC Utrecht), Lykke Sylow (Univ. of Copenhagen), Thomas Weichhart (Medical Univ. of Vienna). Other confirmed speakers: Luc Bertrand (UC Louvain), Morgan Fullerton (Univ. of Ottawa), Remi Mounier (Univ. Claude Bernard Lyon 1), Ganna Panasyuk (Institut Necker Enfants Malades).

In the Atlas

Hongbo ChiThomas Weichhart

Link

Conference site →

Research symposium bringing together junior and senior-level clinical and basic researchers on Tuberous Sclerosis Complex (TSC) to foster exchange of ideas and collaborations.

Why it matters hereTSC (loss of TSC1/TSC2) is a canonical monogenic mTORopathy — constitutive mTORC1 hyperactivation, and the disease itself is the meeting's subject. Organized by the MENTOR MSCA Doctoral Network (mentor-program.eu), which trains 18 PhD candidates on mTOR signaling and mTORopathies; supervisor Alejo Efeyan (CNIO) is already an Atlas author (EFE2012, ZON2011).

Organisers

MENTOR Program (MSCA Doctoral Network, EU grant 101168624) PIs and associated partners

Link

Conference site →

CSHL meeting on the regulation and function of genes and processes known or suspected to control cellular and organismal aging.

Why it matters hereNutrient-sensing longevity pathways (TOR/AMPK/insulin-IGF) are central; organizer William Mair studies TOR/AMPK control of aging in C. elegans - directly adjacent to the Atlas.

Venue

Cold Spring Harbor Laboratory

Organisers

Organizers: Rozalyn Anderson (Univ. Wisconsin–Madison); William Mair (Harvard T.H. Chan); Ashley Webb (Buck Institute).

Speakers

Keynote: Rafael de Cabo (NIA). Confirmed invited speakers: Joseph Baur, Andreas Beyer, Jens Brüning, Weiwei Dang, Jennifer Elisseeff, Judith Frydman, Vadim Gladyshev, Margaret Goodell, Catherine Kaczorowski, Caroline Kumsta, Dudley Lamming, Jodi Nunnari, Courtney Marie Peterson, Marissa Schafer, Ming Xu. Organizers: Rozalyn Anderson, William Mair, Ashley Webb.

In the Atlas

Dudley W. LammingCaroline Kumsta

Link

Conference site →

EMBO Workshop focused on the latest advances in autophagy mechanism and selective autophagy, including roles in metabolism, immunity, and cell differentiation. Organizer: Fulvio Reggiori (Aarhus University).

Why it matters heremTOR is a primary regulator of autophagy induction; speakers including Roberto Zoncu (lysosome/mTOR) ensure direct Atlas relevance. Sessions cover autophagy–mTOR crosstalk in metabolism and disease.

Venue

Kysthotellet, Grenå

Organisers

Organized by: Fulvio Reggiori (Aarhus University), Lisa Frankel, Ian Ganley, Alexandra Stolz. (Updated 2026-07-26: full organizer team now published; previously only Reggiori was listed.)

Speakers

Ian Ganley, Sharon Tooze, Roberto Zoncu, Katja Simon, Louis Lapierre, Carine Joffre

In the Atlas

Ian G. GanleyRoberto Zoncu

Link

Conference site →

Second edition of the FASEB conference on the Hippo pathway, covering mechanisms of Hippo regulation, subcellular dynamics of Hippo signalling, transcriptional regulation in cancer, Hippo in stem cells and regeneration, Hippo in non-cancer disease, and drugging the pathway for cancer treatment. Unpublished data is shared throughout, with a Meet the Expert workshop and a career-development workshop for early-career researchers.

Why it matters hereThe programme is about Hippo, not mTOR, but Kun-Liang Guan (Westlake University, Hangzhou) is one of the four organizers, and he is one of the five researchers the Atlas tracks most closely (10 studies in the corpus). One named programme topic is Hippo crosstalk with other pathways in development and disease, which is where the two growth-control networks meet; Guan's own corpus work sits on the mTOR side of that crosstalk, from amino-acid signalling to the Rag GTPases.

Venue

The Fort Garry Hotel, Spa & Conference Centre

Organisers

Primary organizer Wenqi Wang (University of California, Irvine); Anwesha Dey (Genentech); Kun-Liang Guan (Westlake University, Hangzhou); Kenneth Irvine (Waksman Institute of Microbiology, Rutgers University)

Speakers

Keynote speaker James Martin (Baylor College of Medicine). No further invited-speaker list was published on the conference page; the rest of the programme was built from submitted abstracts.

In the Atlas

Kun-Liang Guan

Link

Conference site →

Held every four years by the TSC Alliance, co-hosted with Tuberous Sclerosis Complex International (TSCi). ~1,000 participants and ~45 sessions spanning research, clinical care, and family programming.

Why it matters hereTSC is the genetic disease that established the TSC1/TSC2 -> Rheb -> mTORC1 axis, and the only indication where an mTOR inhibitor (everolimus) is approved on a directly genetic mTOR rationale (EXIST-1/-2/-3). Anchors the human side of the Atlas's Clinic branch. Atlas authors carrying this evidence: Franz DN, Krueger DA, Bissler JJ, Jozwiak S, Kingswood JC, Bebin EM, Sparagana S, Zonnenberg BA, Belousova E. CAVEAT: mixed research/family conference, not a pure scientific meeting; the TSC Alliance also runs a research-only International TSC Research Conference in off-years, worth tracking separately.

Venue

Gaylord Rockies Resort & Convention Center

Organisers

TSC Alliance, co-hosted with Tuberous Sclerosis Complex International (TSCi)

Speakers

Speaker list not yet resolved against the Atlas Authors table; Linked_Authors deliberately left blank until the program publishes.

Link

Conference site →

Independent, science-led conference on the biology of human longevity bringing together scientists, clinicians, entrepreneurs, investors and policymakers.

Why it matters hereGeneral geroscience/longevity summit; mTOR/nutrient-sensing pathways are a plausible recurring theme given the attendee community (Buck Institute sponsorship, geroscience/biomarkers programming), but not confirmed as a named session topic from the public programme.

Venue

Trinity College Dublin

Organisers

Organized by Longevity Events Dublin; sponsored by the Buck Institute for Research on Aging.

Speakers

Steve Horvath confirmed as a speaker; full speaker roster not resolved as of 2026-09-20 - the official site's Speakers page is a client-rendered app that did not return a text-readable list via fetch.

Link

Conference site →

Meeting bringing together experts at the intersection of metabolism and signal transduction. ~30 invited speakers plus two keynotes, with short talks and poster sessions. Chaired by David Sabatini (IOCB Prague/Boston) and Katerina Rohlenova. A dedicated closing 'mTOR Biology' session features Brendan Manning, Kuang Shen, Mario Pende and David Sabatini, with Michael N. Hall (the discoverer of TOR) giving the second keynote.

Why it matters hereHighest relevance in the calendar. Co-chaired by David Sabatini, keynote by Michael N. Hall (discovered TOR), and an explicit 'mTOR Biology' session. Many speakers are core mTOR/metabolism labs, several of whom are authors in the Atlas corpus.

Venue

National Library of Technology (NTK), Campus Dejvice

Organisers

Chairs: Katerina Rohlenova (Institute of Biotechnology, Czech Academy of Sciences); David Sabatini (IOCB Prague & IOCB Boston). Keynotes: Karen Vousden (Francis Crick Institute); Michael N. Hall (Biozentrum, University of Basel).

Speakers

Keynotes: Karen Vousden, Michael N. Hall. Invited: Janelle Ayres, Liron Bar-Peled, Issam Ben Sahra, Kivanc Birsoy, Anne Brunet, Ralph DeBerardinis, Andrew Dillin, Alejo Efeyan, Mark Febbraio, Lydia Finley, Gerta Hoxhaj, Navdeep Chandel, Heather Christofk, Nada Kalaany, Naama Kanarek, Pekka Katajisto, Brendan Manning, Michael Pacold, Thales Papagiannakopoulos, Erika Pearce, Mario Pende, Richard Possemato, Jared Rutter, Luca Scorrano, Reuben Shaw, Kuang Shen, Celeste Simon, Jessica Spinelli, Eileen White, Omer Yilmaz.

In the Atlas

David M. SabatiniMichael N. HallLiron Bar-PeledAlejo EfeyanGerta HoxhajNada Y. KalaanyBrendan D. ManningReuben J. ShawKuang ShenIssam Ben-SahraAnne BrunetLuca ScorranoMario Pende

Link

Conference site →

Second edition of the FASEB conference on how signalling information is encoded, transmitted and interpreted across space and time, deliberately moving past static pathway diagrams toward a quantitative, spatiotemporal account of signalling. Sessions covered receptor, immune and metabolic signalling, developmental and spatial dynamics, organoids and intravital imaging, biosensors and optogenetic tool development, signalling dynamics in cancer, and cell death, senescence and the cell cycle, with an emphasis on the imaging and modelling methods behind them.

Why it matters heremTOR is named nowhere in the programme; the relevance runs through one keynote speaker and through the method. Jin Zhang (UC San Diego) is a keynote, and he is the author of the Atlas study that first put a FRET biosensor on mTORC1 activity in single living cells – dynamic, time-resolved regulation of mTOR being my current research focus. The sessions on biosensors and optogenetic tool development and on metabolic signalling are the part of this meeting that bears on that question: this is where the instruments for watching the pathway in real time get built, even though the pathway itself is not on the poster.

Venue

Millennium Hotel Maxwell House

Organisers

Mary Teruel (Weill Cornell Medicine); Eric Batchelor (University of Minnesota); Lukasz Bugaj (University of Pennsylvania); Andrew Paek (University of Arizona)

Speakers

Keynote speakers Tobias Meyer (Joseph Hinsey Professor of Cell and Developmental Biology, Weill Cornell Medicine) and Jin Zhang (Professor of Pharmacology, University of California, San Diego). The remaining programme was built from submitted abstracts.

In the Atlas

Jin Zhang

Link

Conference site →

Gordon Research Conference on Systems Aging – systems-level approaches to the biology of aging across species, evolution, reproduction, human longevity and frailty. A companion Gordon Research Seminar (GRS) ran June 13-14, 2026.

Why it matters hereNutrient-sensing and mTOR / insulin-IGF signaling are central pillars of systems-level aging biology featured at this meeting; directly relevant to the Atlas's mTOR-aging axis.

Venue

Grand Summit Hotel, Sunday River

Organisers

Conference chair(s) not yet publicly listed as of July 2026; program under development per GRC site.

Speakers

Speaker list not yet published as of July 2026 — GRC states the detailed program (chair, speakers, discussion leaders) will be posted by Feb 14, 2026. Check https://www.grc.org/systems-aging-conference/2026/ for updates.

Link

Conference site →

Keystone Symposium exploring the reciprocal relationship between cancer and whole-body metabolism, including diet, the microbiome, aging and metabolic disease.

Why it matters hereThe PI3K-AKT-mTOR axis is a central controller of tumor cell growth and metabolism; diet/nutrient inputs that shape tumor metabolism act largely through mTORC1.

Venue

INEC Killarney Convention Centre

Organisers

Scientific organizers: Karen H. Vousden; Cynthia L. Sears; Eileen White.

Speakers

Organizers: Karen H. Vousden, Cynthia L. Sears, Eileen White. Keynote: Heather Christofk. Invited/session speakers: Craig B. Thompson, Matthew G. Vander Heiden, Christopher Halbrook, Bertrand Routy, Saman Maleki, Navdeep S. Chandel, Ayelet Erez, Peter J. Mullen, Ralph J. DeBerardinis, Scott J. Dixon, Richard L. Possemato, Lydia Lynch, Marcus D. Goncalves, Thales Papagiannakopoulos, Mariia Yuneva, Oliver Maddocks, Yanxiang (Jessie) Guo.

In the Atlas

CTCraig B. Thompson

Link

Conference site →

Third annual research meeting of the UK mTOR Pathway Diseases node (NIHR/MRC-funded initiative), convening ~70 researchers, clinicians, industry representatives and patients around the 14 known rare diseases caused by mutations in mTOR-pathway genes (~10,000 people affected in the UK).

Why it matters hereThe only meeting in the calendar organized around mTOR-pathway diseases as its sole subject, not just an adjacent topic. Discovery-science session explicitly covered phosphoproteomics, EV biomarkers, patient-derived assembloids, cellular ageing models, and 'the broader relevance of mTOR signalling across rare and age-related diseases' – directly on-topic for the Atlas's clinic/translation branch. No named external invited-speaker roster was published in the public writeup (a PPIE patient/clinical meeting, not a standard academic program), so Linked_Authors is left empty; node leadership is captured in Organizers instead.

Venue

King's College London

Organisers

Professor Joseph Bateman (lead investigator, Molecular Neuroscience, King's College London); Professor Deb Pal (Paediatric Epilepsy); Dr Laura Mantoan Ritter (Consultant Neurologist); Dr Frances Elmslie (Consultant Clinical Geneticist, St George's); Dr Charlotte Tye (Senior Lecturer in Psychology); Sylvine Lalnunhlimi Butvilauskiene (Research Project Manager).

Speakers

No public named external speaker roster; talks given by node investigators and NHS/registry partners. PPIE Advisory Panel patient representative: Melanie Levy.

Link

Conference site →

54th Annual Meeting of the American Aging Association (AGE). Theme: 'Geroscience: From Discovery to Application.'

Why it matters hereFlagship US geroscience meeting; nutrient-sensing / mTOR biology and rapamycin-class interventions are recurring core topics.

Venue

Utah Valley Convention Center

Organisers

American Aging Association (AGE). Named lectures: Denham Harman Research Award (Steven Austad); AFAR/Cristofalo Award (Marianna Sadagurski); James Joseph/Mark Smith Award (Alberto Espay).

Speakers

Program speakers/chairs incl. Steven Austad (Denham Harman Award Lecture), Rafael de Cabo, Andrzej Bartke, Holly Brown-Borg, Alessandro Bitto (“mTOR inhibition bypasses loss of Complex I activity”), Vishwa Deep Dixit, Marianna Sadagurski (Cristofalo Award), Michael Olivier, Michal Masternak, Liou Sun, Nathan Basisty, Stacy Hussong, Kevin Koronowski, Sarah Ocanas, Cristal Hill. Full program (10 sessions): https://www.americanagingassociation.org/assets/images/2026Meeting/AGE%20Program%20060126.pdf

In the Atlas

Andrzej BartkeHolly M. Brown-BorgAlessandro BittoSHStacy A. Hussong

Link

Conference site →

Joint international autophagy conference organized by three national autophagy research networks – ARCTiC (Norway), SFB1177 (Germany) and Autophagy UK – bringing together ~150 participants for a broad scientific program spanning autophagy molecular mechanisms, selectivity, organelle turnover, trafficking, protein homeostasis, autophagy in biology, human disease and therapeutic targeting.

Why it matters herecore autophagy mechanism meeting; mTORC1 is the master negative regulator of autophagy and several sessions (organelle turnover, protein homeostasis, targeting autophagy) directly engage mTOR-autophagy crosstalk. Speaker roster overlaps heavily with the Atlas's existing autophagy/mTOR author base (Harper, Mizushima, Ganley).

Venue

Holmen Fjordhotell

Organisers

Anne Simonsen (Oslo), Ivan Dikic (Goethe/SFB1177), Sharon Tooze (Francis Crick), Harald Stenmark (Oslo), Tassula Proikas-Cezanne (Tubingen), Ian Ganley (Dundee).

Speakers

Sharon Tooze, Christian Behrends, Viola Nahse, Amos Liang, Helene Knaevelsrud, Brenda Schulman, Terje Johansen, Alexandra Stolz, Simon Wilkinson, Nikolai Engedal, Claudine Kraft, Rupert Beale, Wade Harper (keynote), Anne Simonsen, Ian Ganley, Gerhard Hummer, Anja Bremm, Harald Stenmark, Florian Wilfling, Sylvie Urbe, Christian Munch, Claudio Joazeiro, Alf Hakon Lystad, Dorothee Dormann, Jon Lane, Zvulun Elazar, Noor Gammoh, Tor Erik Rusten, Tassula Proikas-Cezanne, Li Yu, Noboru Mizushima (keynote), Katja Simon, Evandro Fei Fang, Vignir Helgason, Michael Potente, Bernadette Carroll, Jorrit Enserink, Paolo Grumati, Vojo Deretic (keynote)

In the Atlas

J. Wade HarperNoboru MizushimaIan G. GanleyBernadette CarrollChristian BehrendsVojo Deretic

Link

Conference site →

EMBO Workshop on how autophagy integrates with neuronal signaling, metabolism, and disease mechanisms – proteostasis, mitochondrial quality control, synaptic remodeling, neurodegeneration. Follow-up to the 2022 EMBO Workshop 'Brain Autophagy in Health and Disease.'

Why it matters hereAutophagy is a core mTORC1-regulated process; this workshop covers mTOR-linked neuronal proteostasis and autophagy dysfunction in neurodegeneration and aging-related decline, directly relevant to the Atlas's mTOR-autophagy axis.

Venue

Hotel Eden Roc

Link

Conference site →

17th edition of the CSHL meeting on proteostasis: chaperones, the unfolded protein response, co-translational folding and ribosome quality control, biomolecular condensates, and protein clearance via the autophagy-lysosomal pathway and the ubiquitin-proteasome system, with dedicated sessions on aging and neurodegeneration. Partly funded by the National Institute on Aging (grant 1R13AG099698-01).

Why it matters heremTOR is not a named session topic, but the meeting's "Degradation Mechanisms – Autophagy Lysosomal Pathway" and "Organellar Proteostasis and Spatial Quality Control in Aging" sessions sit directly downstream of mTORC1's control of autophagy and lysosomal biogenesis (TFEB). Aging-focused organizers (Malene Hansen, Buck Institute) and chairs (Ana Maria Cuervo, Anne Simonsen, Andrew Dillin) make it adjacent rather than central to the Atlas.

Venue

Cold Spring Harbor Laboratory

Organisers

Organizers: Judith Frydman (Stanford University); Malene Hansen (Buck Institute for Research on Aging); Ursula Jakob (University of Michigan).

Speakers

Session chairs / keynote speakers (CSHL does not publish a full talk roster in advance): F. Ulrich Hartl (MPI Biochemistry), Rick Morimoto (Northwestern), Veena Prahlad (Roswell Park), Ritwick Sawarkar (Cambridge), Rachel Klevit (Univ. Washington), Hideki Taguchi (Institute of Science Tokyo), Claudio Joazeiro (Heidelberg), Marina Rodnina (MPI Biochemistry), Christine Mayr (MSKCC), Florian Wilfling (MPI Biophysics), Ana Maria Cuervo (Albert Einstein), Anne Simonsen (Oslo), Andrew Dillin (UC Berkeley), Kazuhiro Nagata (Kyoto Sangyo), Marc Diamond (UT Southwestern), Aimee Kao (UCSF).

In the Atlas

Ana Maria CuervoMalene Hansen

Link

Conference site →

One-day in-person meeting of the New York Academy of Sciences Cancer and Signaling Discussion Group, co-presented with NYU Langone Health, on how tumour cells exploit signalling and metabolic pathways in the tumour microenvironment to drive malignant growth. Concluded; the 2027 edition of the same recurring meeting is also in the Atlas.

Why it matters hereSame basis as the 2027 successor already in the Atlas: a cancer-metabolism meeting rather than an mTOR meeting. PI3K-AKT-mTOR signalling is standard content in this field but was not named in the announced scope. Listed for the record because this is the edition Brendan Manning and Christian Dibble referenced on Bluesky — neither is named on any official NYAS page, so their involvement is unconfirmed (same caveat as the 2027 record).

Organisers

New York Academy of Sciences, Cancer and Signaling Discussion Group; lead sponsor Pfizer; co-presented with NYU Langone Health.

Speakers

Checked 16 Sep 2026: the events.nyas.org speaker sub-page for this concluded edition returns 404 and no archived speaker list was found. Surfaced because Brendan Manning and Christian Dibble both referenced this edition on Bluesky — neither is named on any official page, so treat their involvement as unconfirmed.

Link

Conference site →

Keystone Symposia conference on the role of the immune system in aging and its impact on organ health, longevity and rejuvenation. Held jointly with the Keystone Symposium on Innate Immunity: Diversity in Host Defense and Disease. Sessions covered targeting innate immunity for healthy aging, inflammation/senescence, organ regeneration and aging, inflammaging, organ-organ communication and systemic aging, and biomarkers/aging clocks/human longevity.

Why it matters hereNot an mTOR-focused meeting, but a top-tier geroscience venue whose organisers and speakers set the framing for nutrient-sensing and gerotherapeutic work the Atlas tracks (senescence, inflammaging, rejuvenation, aging clocks). Relevance to mTOR is indirect: no session on the programme addresses mTORC1/mTORC2 or rapamycin directly.

Venue

Fairmont Banff Springs

Organisers

Scientific Organizers: Anne Brunet (Stanford University); Eric M. Verdin (Buck Institute for Research on Aging); Manuel Serrano (Altos Labs); P. Eline Slagboom (Leiden University). Joint welcome remarks with Kate Schroder (University of Queensland).

Speakers

Keynote: Beth Stevens (Boston Children's Hospital/HMS). Speakers: Katrin Andreasson (Stanford); Emily Goldberg (UCSF); Oliver Hahn (Calico); Cecilia G de Magalhaes (BWH/HMS); Susan B Carpenter (UC Santa Cruz); Byron F Mobbs (IMB, Univ. Queensland); Noga Ron-Harel (Technion); Anne Schaefer (MPI Biology of Ageing); Vishwa Deep Dixit (Yale); Manuel Serrano (Altos Labs); Margaret A Goodell (Baylor); Anne Brunet (Stanford); Thomas A Rando (UCLA); Sofia Vieto (Yale); Anja Michl (Helmholtz Munich); Michael Segel (Harvard); Andrea Ablasser (EPFL); Vishva M Dixit (Genentech); Eicke Latz (DRFZ); Julia Belk (Stanford); Kirsten Kenney (IMB); Itamar Harel (Hebrew Univ.); Andrew G Dillin (UC Berkeley); Dario Riccardo Valenzano (Leibniz Institute on Aging); Maria Mittelbrunn (CBM, CSIC); John C Martinez (Rochester); Vadim Gladyshev (BWH/HMS); Jingdong Jackie Han (Peking Univ.); P. Eline Slagboom (Leiden); Eric M Verdin (Buck Institute). Plus short talks and symposia-spotlight speakers listed on the on-page programme.

In the Atlas

Anne Brunet

Link

Conference site →

GRC on core autophagy machinery and its roles in cancer, aging, neurodegeneration, infectious disease and development.

Why it matters heremTORC1 is the master negative regulator of autophagy; this GRC directly covers the mechanistic and disease biology of the autophagy pathway central to the Atlas's autophagy/lysosome arm. Confirmed 2026 program includes a dedicated talk on "The TFEB-mTORC1 Axis in Tumorigenesis."

Venue

Ventura Beach Marriott

Organisers

Chairs and vice chairs confirmed on the GRC site as of the conference (Mar 15-20, 2026), but GRC renders names as images (anti-scraping), so they cannot be captured in text form. Conference has concluded; names remain unresolved from public text sources as of 2026-07-22.

Link

Conference site →

Keystone Symposium on mitochondria as signaling organelles that control cellular and organismal physiology, and how mitochondrial dysfunction drives disease.

Why it matters hereMitochondrial metabolism and nutrient status are tightly integrated with mTORC1 signaling; mitochondrial cues feed into growth control central to the Atlas. Downgraded to Tier 3: mTOR is not a named topic anywhere in the program – the connection is inferred adjacency (mitochondrial cues feeding nutrient sensing), not stated content. Retained for completeness, not prioritised.

Venue

Keystone Resort

Organisers

Scientific organizers: Navdeep S. Chandel; Aleksandra Trifunovic.

Speakers

Organizers: Navdeep S. Chandel, Aleksandra Trifunovic. Keynote: Anu Suomalainen Wartiovaara. Invited/session speakers: Elena Ziviani, Kivanc Birsoy, Dipayan Chaudhuri, Dustin Hancks, Xin Jie Chen, Phillip West, María Mittelbrunn, Lena Pernas, Michelle Clasquin, Andrew G. Dillin, Jose Antonio Enríquez, Peter M. Douglas, Dave Pagliarini, Prashant Mishra, Reuben J. Shaw, Jan Riemer, Marcia C. Haigis, Jay H. Chung, Janine Santos, Liron Bar-Peled, Mike P. Murphy.

In the Atlas

Liron Bar-PeledReuben J. Shaw

Link

Conference site →

Keystone Symposium covering the roles and mechanisms of autophagy across health and disease, spanning basic, translational and clinical research plus industry developments. Held jointly with the Keystone symposium 'Membrane Dynamics, Repair and Disease' to enable cross-talk.

Why it matters heremTORC1 is the master negative regulator of autophagy; sessions address mTOR inhibition and nutrient control of autophagic flux. Directly relevant to the autophagy/lysosome arm of the Atlas.

Venue

Keystone Resort

Organisers

Scientific organizers: Anne Simonsen; Sharon A. Tooze; Dan Baird.

Speakers

Organizers: Anne Simonsen, Sharon A. Tooze, Dan Baird. Keynotes: Erika L. Holzbaur, Harald Stenmark. Invited/session speakers: Felix Randow, Oliver Florey, Jayanta Debnath, Rupert Beale, Maho Hamasaki, Zvulun Elazar, J. Wade Harper, Phyllis Hanson, James H. Hurley, Claudio Bussi, Ivan Dikic, Ai Yamamoto, Joseph D. Mancias, Anastasia Henry, Chris Shoemaker, Simon Wilkinson, Michael Lazarou, Chantell S. Evans, Martin Graef.

In the Atlas

James H. HurleyJayanta DebnathJ. Wade HarperSTSharon A. Tooze

Link

Conference site →

Fourth edition of a deliberately small cancer-metabolism meeting run by the CLIP metabolic study group at the Second Faculty of Medicine, Charles University, co-organised by the Institute of Biotechnology of the Czech Academy of Sciences. The limited-attendance format is the point: it is built for exchange between students, researchers and clinicians rather than for a large audience. A Seahorse user meeting at BIOCEV followed on 16 October.

Why it matters heremTOR is not in the programme title, which is cancer metabolism, but David Sabatini is a listed invited speaker and he is one of the five researchers the Atlas tracks most closely (48 studies in the corpus). His speaker biography on the symposium page is almost entirely mTOR: the discovery of the kinase, mTORC1 and mTORC2, and nutrient signalling to mTORC1 through the lysosomal Rag GTPases. Notable for the Atlas as the Prague meeting Sabatini spoke at from his IOCB Prague base, alongside the separate Prague Metabolism and Signaling Symposium already curated here.

Venue

Plzeňská Campus, Pelouch Lecture Hall

Organisers

CLIP – metabolic study group, Second Faculty of Medicine, Charles University; co-organiser Institute of Biotechnology, Czech Academy of Sciences

Speakers

Invited speakers as listed: David Sabatini (IOCB Boston & Prague), Arkaitz Carracedo (CIC bioGUNE / Ikerbasque), Kristýna Gloc Pimková, Katerina Rohlenova (Institute of Biotechnology CAS), Petra Beran Holečková, Francesca Matteini, Alena Pecinová, Libor Macurek, Jaroslav Truksa, Štěpánka Boukalová, Petr Heneberg. The organisers kept the heading marked "(will be completed)", so the list may not be the final one.

In the Atlas

David M. SabatiniArkaitz Carracedo

Link

Conference site →

The LAM Foundation's marquee event: a dual-track meeting combining a scientific research conference (>100 researchers and clinicians) with a patient and family conference; >300 attendees. Held every two to three years in rotating locations. NEXT EDITION NOT YET ANNOUNCED as of July 2026 - this record documents the 2025 edition; add the next edition when dated.

Why it matters hereLAM is the second approved mTOR-inhibitor indication (sirolimus, via the MILES trial) and the only disease in the world whose standard of care IS mTOR inhibition. The single most concentrated venue for human sirolimus efficacy and long-term safety data. Atlas authors: McCormack FX, Moss J.

Venue

Westin Kansas City at Crown Center

Organisers

The LAM Foundation

Speakers

Speaker list not resolved against the Atlas Authors table; Linked_Authors deliberately left blank.

Link

Conference site →

The 12th Aging Research and Drug Discovery meeting – the largest translational geroscience conference – convening academics, biotech founders, pharma and clinicians over a five-day hybrid event on the biology of aging and drug development.

Why it matters hereRapamycin/mTOR inhibition is one of the central pillars of aging pharmacology; geroscience translation of mTOR is a recurring theme of ARDD and directly informs the Atlas gap/hypothesis layer.

Venue

Ceremonial Hall, University of Copenhagen

Organisers

Organized by the University of Copenhagen (Scheibye-Knudsen group) and partners.

Speakers

Speakers/participants included David Sinclair (Harvard), Marco Demaria, Kristen Fortney (BioAge), Morten Meldal (Nobel laureate), Andrew Adams (Eli Lilly), among many others.

Link

Conference site →

Biennial international research conference of the TSC Alliance, subtitled 'Engage, Accelerate, Transform', bringing basic, translational and clinical researchers together on tuberous sclerosis complex and the overlapping disorders it touches: epilepsy, autism and TSC-associated neuropsychiatric disorders (TAND), lymphangioleiomyomatosis (LAM), renal disease and cancer. Four plenary sessions over three days, plus mini-symposia on TAND, TSC disease mechanisms and genetics, and LAM and angiomyolipomas. The next edition is scheduled for 16–18 September 2027 at the same venue.

Why it matters hereTSC is an mTOR disease in the strictest sense: loss of the TSC1/TSC2 complex removes the brake on mTORC1, and the resulting hyperactivation drives the tumours, the epilepsy and much of the neurological phenotype. The clinical use of rapalogs in TSC is the closest the field comes to mTOR inhibition as licensed medicine. Brendan Manning, one of the five researchers the Atlas tracks most closely, gave a plenary talk on 28 June titled 'Metabolic Effects of mTOR in Tumors, the Tumor Microenvironment, and Host'. Mustafa Sahin (Boston Children's Hospital), whose TSC neurobiology work is in the corpus, spoke in the TAND plenary on 'Investigating TAND and Epilepsy Using Human Neurons'. Several other talks name mTOR directly, among them TREK1 inhibition by mTOR and mTOR-LPL-driven lipid metabolism in TSC microglia.

Venue

Bethesda North Marriott Hotel & Conference Center, Rockville

Organisers

Hosted by the TSC Alliance (Kari Luther Rosbeck, President and CEO; Steven L. Roberds, Chief Scientific Officer; Dean J. Aguiar, Vice President, Translational Research). Plenary session moderators: Kate Richardson and Carmen Priolo (Session 1); Howard Weiner and Kimberly Raab-Graham (Session 2); Rajsekar Rajaraman and Shafali Jeste (Session 3); Uchenna Unachukwu and Nicola Alesi (Session 4).

Speakers

Plenary speakers as printed in the conference agenda. Session 1 (26 Jun, LAM, renal disease and adult care): William Stanford, Yan Tang, Flaviane Silva, Simon Johnson, Manoocher Soleimani, Lara Friel, David Ritter, Diego Maciel-Lima, Laura Gorecki, Amber Goedken. Session 2 (27 Jun, epilepsy): Lisa Julian, Darcy Krueger, Zin-Juan Klaft, Eleonora Aronica, Nina Gruetzmacher, S. Katie Ihnen, with Elizabeth Thiele and Priyamvada Tatachar in the Q&A. Session 3 (28 Jun, TAND): Mustafa Sahin, Kirstin Risgaard, Jamie Capal, Nola Chambers, Kate Fifield, Elizabeth Thiele, Nicole McDonald. Session 4 (28 Jun, TSC biology): Rebecca Ihrie, Elizabeth Henske, Brendan Manning, Weibo Niu, Peter Crino. Mini-symposia co-chairs: Jamie Capal and Anna Jansen (TAND); Laura Farach and Lisa Julian (disease mechanisms and genetics); Nishant Gupta and Lyndsay Harshman (LAM and angiomyolipomas).

In the Atlas

Brendan D. ManningMustafa Sahin

Link

Conference site →

Keystone Symposium 'Autophagosomes and Endolysosomes: From Fundamental Mechanisms to Disease Implications', spanning the biogenesis and function of autophagosomes and the endolysosomal system through to disease.

Why it matters hereThe lysosomal surface is the physical platform for mTORC1 activation (Rag GTPases, Ragulator) and the TFEB axis; endolysosomal biology is core mechanistic ground for the Atlas.

Venue

Fairmont Chateau Whistler

Organisers

Scientific organizers: Christina Towers; Rupert Beale; Leon O. Murphy.

Speakers

Organizers/speakers: Christina Towers, Rupert Beale, Leon O. Murphy (full speaker list on the Keystone site).

Link

Conference site →