4 scientists over 3 generations of training, 1998–2013.
The family starts with Craig B. Thompson.
The lab with the most trainees here is Craig B. Thompson's,
with 2 people in this tree.
4 of the 4 have a full profile in the Atlas. Positions and dates come from
the sources listed under each person and can lag behind job moves.
What the family's own labs work on
Immunity 2
Metabolism 1
The tree
Read left to right: each line means "trained in this lab". Names with a profile are links.
Dashed rings mark people without a profile yet. Open it in the interactive map →
Postdoc, about 1998-2003 (University of Chicago, then University of Pennsylvania)
In the labShowed that lymphocytes deprived of growth signals lose the glucose transporter Glut1, shrink and then die, so outside signals keep cells alive partly by controlling nutrient uptake (Mol Cell 2000).
Own labRathmell Lab, Ben May Department for Cancer Research, University of Chicago (Chicago, Illinois, USA). He studies how immune cells get and use fuel, and how that decides whether they fight or calm down.Immunometabolism: how nutrients and metabolic pathways control T cell activation, inflammation and anti-tumor immunity.
Postdoc, about 2003-2008 (University of Pennsylvania)
In the labShowed that AMPK triggers a p53-dependent metabolic checkpoint that halts cell division when glucose is low (Mol Cell 2005).
Own labJones Lab, Department of Metabolism and Nutritional Programming, Van Andel Institute (Grand Rapids, Michigan, USA). He studies how immune cells and cancer cells get their energy, and how that changes how well they work.Cancer metabolism and immunometabolism: how T cells and tumour cells fuel themselves, including AMPK and mTOR signalling.
In the labShowed that effector CD4 T cells (Th1, Th2, Th17) run on glucose while regulatory T cells burn fat, and that AMPK activation tips cells toward Tregs (J Immunol 2011); also found ERR-alpha as a metabolic regulator of effector T cells (PNAS 2011).
Own labMetabolon, Inc. (Durham, North Carolina, USA). He showed that different types of helper T cells use different fuels, sugar or fat.T cell metabolism; later metabolomics in industry.
How links are chosen: a link appears only when two independent sources agree, a PubMed
paper the trainee wrote with the mentor at the mentor's institution and a separate page naming the mentor.
More on the method.
