Kendall J. Condon
Ran genome-wide CRISPR screens revealing how mitochondrial stress signals to mTORC1
Undergrad research in enzyme chemical biology (2014–2015) · PhD, MIT (Sabatini lab; thesis defended March 2021) · now in industry (Bristol Myers Squibb per a public profile, title unverified)
PhD (Sabatini lab), MIT Department of Biology ↗
Fourth author on GU2017 (SAMTOR). Her own thesis (CON2021, PNAS) used genome-wide CRISPR-Cas9 screens to catalogue mTORC1 regulators, converging on mitochondrial function: AMPK and HRI relay mitochondrial distress to mTORC1 on different timescales.
Undergrad chemical biology work included collaborators like Kevan Shokat (DDX3 helicase inhibitors).
Public profile suggests move to Bristol Myers Squibb — not independently confirmed.
Milestones in the Atlas
| Year | Evidence | Study |
|---|---|---|
| 2017 | M | SAMTOR is an S-adenosylmethionine sensor for the mTORC1 pathway GU2017 Contributed to SAMTOR biochemistry as a graduate student. |
| 2021 | M | Genome-wide CRISPR screens reveal multitiered mechanisms through which mTORC1 senses mitochondrial dysfunction CON2021 Led CRISPR screens showing AMPK and HRI relay mitochondrial dysfunction to mTORC1. |