Making new contacts: the mTOR network in metabolism and signalling crosstalk

More than 20 years after its discovery, our understanding of target of rapamycin (TOR) signalling continues to grow. Recent global omics studies have revealed physiological roles of mammalian TOR (mTOR) in protein, nucleotide and lipid synthesis. Furthermore, emerging evidence provides new insight into the control of mTOR by other pathways such as Hippo, WNT and Notch signalling. Together, this progress has expanded the list of downstream effectors and upstream regulators of mTOR signalling.

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Shimobayashi, M., et al. (2014). Making new contacts: the mTOR network in metabolism and signalling crosstalk. Nature reviews. Molecular cell biology. https://doi.org/10.1038/nrm3757

@article{SHI2014,
  author       = {Shimobayashi, M. and Hall, M. N. and others},
  title        = {{Making new contacts: the mTOR network in metabolism and signalling crosstalk}},
  journal      = {Nature reviews. Molecular cell biology},
  year         = {2014},
  doi          = {10.1038/nrm3757},
  note         = {PMID: 24556838},
}

Cite this Atlas record

The record is the Atlas's own work — the evidence label, the extracted findings and the links. It is cited as part of the dataset, not as the paper.

Barton, O. (2026). Oliver's mTOR Atlas (record SHI2014) [Data set]. https://mtor-atlas.org/study/SHI2014/ · Dataset DOI 10.5281/zenodo.22059963

@misc{atlas_SHI2014,
  author       = {Barton, Oliver},
  title        = {{Oliver's mTOR Atlas}, record SHI2014},
  howpublished = {Data set},
  year         = {2026},
  url          = {https://mtor-atlas.org/study/SHI2014/},
  doi          = {10.5281/zenodo.22059963}
}