Maureen R. Horton
Pulmonary physician-scientist who studies immune mechanisms of lung inflammation and fibrosis
Associate Professor of Medicine · Johns Hopkins University School of Medicine · ASCI member
Portrait: American Society for Clinical Investigation
Maureen Horton is Associate Professor of Medicine in the Division of Pulmonary and Critical Care Medicine at Johns Hopkins University School of Medicine and an elected member of the American Society for Clinical Investigation. Her research looks at immune mechanisms of lung inflammation and scarring, including the extracellular matrix and metabolic changes driven by mTORC2.
In the Atlas she is senior author of POW2011, an Annual Review of Immunology article with Jonathan Powell on how mTOR links the metabolism of immune cells to the decisions they make about what kind of cell to become.
Milestones in the Atlas
A selection, not a full bibliography: only papers that meet the Atlas inclusion criteria.
| Year | Evidence | Study |
|---|---|---|
| 2011 | A | The kinase mTOR regulates the differentiation of helper T cells through the selective activation of signaling by mTORC1 and mTORC2 DEL2011 mTORC1 and mTORC2 selectively program distinct CD4 helper T-cell lineages. |
| 2011 | R | Regulation of immune responses by mTOR POW2011 Senior author: review of mTOR as an integrator of immune-cell metabolism and differentiation. |
Co-authors in the Atlas 4
People with a profile here who share at least one study with Maureen R. Horton.
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- Jonathan D. Powell 2 shared studies Showed that T cells lacking mTOR become regulatory T cells instead of effector cells, and that mTORC1 and mTORC2 each steer a different type of helper T cell
- Adam T. Waickman Immunologist who trained in Jonathan Powell's mTOR and T cell lab at Johns Hopkins and now studies human immune responses to dengue virus at SUNY Upstate Medical University
- Greg M. Delgoffe Showed as a graduate student in Jonathan Powell's lab that T cells lacking mTOR become regulatory rather than effector T cells, and that mTORC1 and mTORC2 steer different helper-T-cell fates
- Kristen N. Pollizzi Immunologist trained in Jonathan Powell's lab at Johns Hopkins who used gene deletions in mice to show how the two mTOR complexes push killer T cells toward effector or memory fates
Every researcher with a profile →
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