Annika G. Sonntag
Experimental researcher in the Thedieck group who contributed cell data to the dynamic mTOR network model and the AMPK–mTOR amino acid study.
Scientist, Discovery, Immatics Biotechnologies (Tübingen, since 2014) · doctoral research, Institute of Biology III, University of Freiburg (Thedieck group)
Portrait: Illumina iCommunity interview (Immatics Biotechnologies)
Sonntag is second author on the 2012 dynamic model of insulin–mTOR signalling, which combined her group's cell experiments with modelling from Newcastle (DAL2012), and a co-author on the 2016 study of concurrent AMPK and mTOR activation by amino acids (DAL2016). In 2012 she was also first author of a related FEBS Journal paper on IRS-dependent regulation of AMPK by insulin.
The 2012 University of Freiburg press release names her as a researcher at the Institute of Biology III. In 2014 she moved to the Tübingen immuno-oncology company Immatics Biotechnologies, where she built the RNA-sequencing pipeline and leads NGS-based HLA typing for its tumour-specific immunotherapies.
Milestones in the Atlas
A selection, not a full bibliography: only papers that meet the Atlas inclusion criteria.
| Year | Evidence | Study |
|---|---|---|
| 2012 | M | A dynamic network model of mTOR signaling reveals TSC-independent mTORC2 regulation DAL2012 Second author: experimental data for the dynamic insulin–mTOR network model. |
| 2016 | M | A systems study reveals concurrent activation of AMPK and mTOR by amino acids DAL2016 Co-author on the systems study of amino acid activation of AMPK and mTOR. |
Co-authors in the Atlas
People with a profile here who share at least one study with Annika G. Sonntag.
- Daryl P. Shanley 2 shared studies Systems biologist of ageing whose Newcastle modelling group built, with the Thedieck lab, the dynamic models of mTOR signalling in the Atlas.
- Kathrin Thedieck 2 shared studies Senior author of three Atlas studies that treat mTOR signalling as a dynamic network: TSC-independent mTORC2 activation, concurrent AMPK and mTOR activation by amino acids, and G3BP tethering of TSC to lysosomes.
- Piero Dalle Pezze 2 shared studies First author of two Atlas modelling studies: the dynamic insulin–mTOR network model (TSC-independent mTORC2) and the systems study of concurrent AMPK and mTOR activation by amino acids.
- Mirja Tamara Prentzell First author of the study showing that G3BP proteins anchor the TSC complex to lysosomes, a physical brake on mTORC1; earlier co-author on the dynamic insulin–mTOR network model.
- Ralf Baumeister Head of the Freiburg department that hosted the Thedieck group during the mTOR network modelling work; co-author on the dynamic mTOR model and the G3BP–TSC study.
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