Glutamine alleviates bisphenol A-induced jejunal injury in piglets involving mitochondrial function restoration and AMPK-mTOR signaling regulation.

Bisphenol A (BPA) disrupts intestinal homeostasis and promotes epithelial injury in piglets. Glutamine (Gln) is a vital energy substrate for intestinal epithelial cells. Piglet and porcine intestinal epithelial cell models were used. BPA exposure impaired intestinal morphology and barrier integrity, with reduced tight junction protein expression, decreased epithelial renewal capacity, altered JNK/MAPK signaling and disrupted mitochondrial structure and energy metabolism.

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Xie, J., et al. (2026). Glutamine alleviates bisphenol A-induced jejunal injury in piglets involving mitochondrial function restoration and AMPK-mTOR signaling regulation. Ecotoxicology and Environmental Safety. https://doi.org/10.1016/j.ecoenv.2026.120698

@article{XIE2026,
  author       = {Xie, J. and Liu, Z. and Liu, W. and others},
  title        = {{Glutamine alleviates bisphenol A-induced jejunal injury in piglets involving mitochondrial function restoration and AMPK-mTOR signaling regulation}},
  journal      = {Ecotoxicology and Environmental Safety},
  year         = {2026},
  doi          = {10.1016/j.ecoenv.2026.120698},
}

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The record is the Atlas's own work — the evidence label, the extracted findings and the links. It is cited as part of the dataset, not as the paper.

Barton, O. (2026). Oliver's mTOR Atlas (record XIE2026) [Data set]. https://mtor-atlas.org/study/XIE2026/ · Dataset DOI 10.5281/zenodo.22059963

@misc{atlas_XIE2026,
  author       = {Barton, Oliver},
  title        = {{Oliver's mTOR Atlas}, record XIE2026},
  howpublished = {Data set},
  year         = {2026},
  url          = {https://mtor-atlas.org/study/XIE2026/},
  doi          = {10.5281/zenodo.22059963}
}