The PI3K-AKT network at the interface of oncogenic signalling and cancer metabolism

The altered metabolic programme of cancer cells facilitates their cell-autonomous proliferation and survival. In normal cells, signal transduction pathways control core cellular functions, including metabolism, to couple the signals from exogenous growth factors, cytokines or hormones to adaptive changes in cell physiology.

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Hoxhaj, G., et al. (2019). The PI3K-AKT network at the interface of oncogenic signalling and cancer metabolism. Nature reviews. Cancer. https://doi.org/10.1038/s41568-019-0216-7

@article{HOX2019,
  author       = {Hoxhaj, G. and Manning, B. D. and others},
  title        = {{The PI3K-AKT network at the interface of oncogenic signalling and cancer metabolism}},
  journal      = {Nature reviews. Cancer},
  year         = {2019},
  doi          = {10.1038/s41568-019-0216-7},
  note         = {PMID: 31686003},
}

Cite this Atlas record

The record is the Atlas's own work — the evidence label, the extracted findings and the links. It is cited as part of the dataset, not as the paper.

Barton, O. (2026). Oliver's mTOR Atlas (record HOX2019) [Data set]. https://mtor-atlas.org/study/HOX2019/ · Dataset DOI 10.5281/zenodo.22059963

@misc{atlas_HOX2019,
  author       = {Barton, Oliver},
  title        = {{Oliver's mTOR Atlas}, record HOX2019},
  howpublished = {Data set},
  year         = {2026},
  url          = {https://mtor-atlas.org/study/HOX2019/},
  doi          = {10.5281/zenodo.22059963}
}