Pathway link MTORC2-SGK1

mTORC2 → SGK1

mTORC2 activates SGK1.

SGK1 is a second target of mTORC2 alongside Akt, and it shares some of Akt's jobs.

SGK1 is a second mTORC2 substrate alongside Akt, and it carries some of the functions usually credited to Akt.

The conditions it holds under

Single-study edge in this corpus.

Time it takes

minutes

Step

direct (one molecule acts on the other)

Measured in

mammalian cells

Where in the cell

cytosol

Reaches people?

plausible in people, not shown directly

How settled

emerging, few independent studies

Studies behind it

Points the other way

No study in the Atlas contradicts this link. That means none in this curated set, not none in the literature.

Who has checked this

Checked by

No researcher outside the project has checked this link yet.

Curator sign-off

Not signed off yet. This link was drafted with AI help and has not been reviewed link by link; treat it as a proposal until it is.

Curated by

Oliver Barton, with AI help for drafting; see how links are checked.

“How settled” describes how far researchers in the field agree. It is not the same as the sign-off above, which only says whether a named curator has checked this page.

If this link rests on your own work: a click on “This looks right” below, or a short note through “Report an error”, helps us more than anything else on this page.

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