Shuai Yu
Neurology researcher who contributed to a study showing that the lipid kinase PIP4K2A protects the brain after ischaemic stroke by relieving a block on autophagy and boosting AKT/mTOR signalling
Department of Neurology · The Affiliated Suzhou Hospital of Nanjing Medical University · Suzhou Municipal Hospital · Gusu School, Nanjing Medical University · Suzhou, Jiangsu, China
Shuai Yu is part of the clinical neurology research group at Suzhou Municipal Hospital that studies mechanisms of ischemic stroke. The study behind this entry found that PIP4K2A is elevated in stroke patients' blood and, in mouse models, acts as a protective factor: raising PIP4K2A reduced a stress complex (TRIB3-p62) that otherwise clogs up autophagy, restored autophagic flux, and was accompanied by stronger AKT/mTOR signaling — together limiting brain damage and improving recovery.
PubMed shows Yu as a recurring member of this Suzhou stroke-research team, also contributing to other 2025–2026 studies on intracerebral hemorrhage biomarkers and basilar-artery stroke thrombectomy outcomes from the same hospital.
Milestones in the Atlas
A selection, not a full bibliography: only papers that meet the Atlas inclusion criteria.
| Year | Evidence | Study |
|---|---|---|
| 2026 | A | PIP4K2A Attenuates Cerebral Ischemia/Reperfusion Injury by Reducing the TRIB3-p62 Complex Burden and Modulating AKT/mTOR Signaling. MA2026 Contributed to the Suzhou Municipal Hospital team's work showing PIP4K2A reduces the TRIB3-p62 autophagy block and boosts AKT/mTOR signaling after cerebral ischemia/reperfusion injury. |
Co-authors in the Atlas 4
People with a profile here who share at least one study with Shuai Yu.
ShowHide
- Bodun Ma Neurology researcher in Suzhou and first author of a 2026 study on how the enzyme PIP4K2A protects the brain after stroke by restoring autophagy through AKT/mTOR
- Hongxuan Feng Neurologist at Suzhou Municipal Hospital and senior author of a 2026 stroke study proposing PIP4K2A as a protector of brain tissue through AKT/mTOR signalling and autophagy
- Mei Li Scientist at the Pediatrics Research Institute of Children's Hospital of Soochow University studying brain injury, who contributed to a study of how PIP4K2A protects the brain after stroke
- Xiaotian Yu Stroke neurology researcher who contributed to a study of how PIP4K2A limits brain injury after ischaemia and reperfusion through the TRIB3–p62 and AKT–mTOR pathways
Every researcher with a profile →
Thank you. That helps us know which pages have been read by someone who knows the work.
Thank you. We will check it and correct the page.
Thank you. Your answer was counted anonymously.