Testosterone propionate maintains autophagic flux and mitochondrial integrity via regulation of the LC3B/p62/Beclin-1/mTOR axis in induced liver fibrosis.

In a CCl4-induced chronic liver injury rat model, testosterone propionate was found to preserve autophagic flux and mitochondrial function. Androgen deprivation worsened hepatic damage, while testosterone treatment maintained the LC3B/p62/Beclin-1/mTOR axis and protected mitochondrial quality control and reduced apoptosis.

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Verma, S., Vaishnav, S., Yadav, M., Verma, A., & Washimkar, K. (2026). Testosterone propionate maintains autophagic flux and mitochondrial integrity via regulation of the LC3B/p62/Beclin-1/mTOR axis in induced liver fibrosis. Journal of Molecular Histology. https://doi.org/10.1007/s10735-026-10905-0

@article{VER2026,
  author       = {Verma, S. and Vaishnav, S. and Yadav, M. and Verma, A. and Washimkar, K.},
  title        = {{Testosterone propionate maintains autophagic flux and mitochondrial integrity via regulation of the LC3B/p62/Beclin-1/mTOR axis in induced liver fibrosis}},
  journal      = {Journal of Molecular Histology},
  year         = {2026},
  doi          = {10.1007/s10735-026-10905-0},
  note         = {PMID: 42461311},
}

Cite this Atlas record

The record is the Atlas's own work — the evidence label, the extracted findings and the links. It is cited as part of the dataset, not as the paper.

Barton, O. (2026). Oliver's mTOR Atlas (record VER2026) [Data set]. https://mtor-atlas.org/study/VER2026/ · Dataset DOI 10.5281/zenodo.22059963

@misc{atlas_VER2026,
  author       = {Barton, Oliver},
  title        = {{Oliver's mTOR Atlas}, record VER2026},
  howpublished = {Data set},
  year         = {2026},
  url          = {https://mtor-atlas.org/study/VER2026/},
  doi          = {10.5281/zenodo.22059963}
}