Sirolimus is effective for paediatric Evans syndrome and secondary autoimmune cytopenias: A retrospective cohort study.

McNeill M, Cellarius C, Illamperuma N, Zipper R, Carcao C, Baker JM, Butchart S, Fantauzzi M, Malcolmson C, Pabari R, Rollan D, …, Carcao M · 2026 · British Journal of Haematology · Atlas ID MCNEILL2026

What this study shows

Retrospective single-centre paediatric cohort reporting that sirolimus is effective in paediatric Evans syndrome and secondary autoimmune cytopenias. Abstract not yet indexed — effect sizes to be confirmed.

Abstract

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[Abstract not available in the PubMed record at time of retrieval, 29 Aug 2026.]

Read the full abstract on PubMed →

At a glance

Evidence type	H Human study Marked H because it is direct evidence from a human clinical trial or human cohort; the code names the kind of study, not its quality -- a small, well-run trial is still H.
Study type	3 - Human Observational
Model system	Human (paediatric retrospective cohort)
Journal	British Journal of Haematology
Year	2026
Peer reviewed	Yes
Record last updated	2026-10-01
Source	DOI 10.1111/bjh.70795 · PMID 42655953

Extracted findings

These fields were extracted from the paper with AI assistance and have not been checked against the source. Read them as a pointer into the paper, not as curated claims; where they disagree with the curated summary above, the curated summary stands.

Intervention	Sirolimus
Target	mTOR
Model	Human
Effect	Reported effective for paediatric Evans syndrome and secondary autoimmune cytopenias

In the Atlas

Cite this paper

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McNeill, M., Cellarius, C., Illamperuma, N., Zipper, R., Carcao, C., Baker, J. M., Butchart, S., Fantauzzi, M., Malcolmson, C., Pabari, R., Rollan, D., Qu, K., & Carcao, M. (2026). Sirolimus is effective for paediatric Evans syndrome and secondary autoimmune cytopenias: A retrospective cohort study. British Journal of Haematology. https://doi.org/10.1111/bjh.70795

@article{MCNEILL2026,
  author       = {McNeill, M. and Cellarius, C. and Illamperuma, N. and Zipper, R. and Carcao, C. and Baker, J. M. and Butchart, S. and Fantauzzi, M. and Malcolmson, C. and Pabari, R. and Rollan, D. and Qu, K. and Carcao, M.},
  title        = {{Sirolimus is effective for paediatric Evans syndrome and secondary autoimmune cytopenias: A retrospective cohort study}},
  journal      = {British Journal of Haematology},
  year         = {2026},
  doi          = {10.1111/bjh.70795},
  note         = {PMID: 42655953},
}

Cite this Atlas record

The record is the Atlas's own work — the evidence label, the extracted findings and the links. It is cited as part of the dataset, not as the paper.

Barton, O. (2026). Oliver's mTOR Atlas (record MCNEILL2026) [Data set]. https://mtor-atlas.org/study/MCNEILL2026/ · Dataset DOI 10.5281/zenodo.22059963

@misc{atlas_MCNEILL2026,
  author       = {Barton, Oliver},
  title        = {{Oliver's mTOR Atlas}, record MCNEILL2026},
  howpublished = {Data set},
  year         = {2026},
  url          = {https://mtor-atlas.org/study/MCNEILL2026/},
  doi          = {10.5281/zenodo.22059963}
}

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