Oliver's mTOR Atlas Evidence Platform
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Sirolimus is effective for paediatric Evans syndrome and secondary autoimmune cytopenias: A retrospective cohort study.

McNeill M, Cellarius C, Illamperuma N et al. · 2026 · British Journal of Haematology · Atlas ID MCNEILL2026

What this study shows

Retrospective single-centre paediatric cohort reporting that sirolimus is effective in paediatric Evans syndrome and secondary autoimmune cytopenias. Abstract not yet indexed — effect sizes to be confirmed.

Abstract

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[Abstract not available in the PubMed record at time of retrieval, 29 Aug 2026.]

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At a glance

Evidence type H Human study Marked H because it is direct evidence from a human clinical trial or human cohort; the code names the kind of study, not its quality -- a small, well-run trial is still H.
Study type3 - Human Observational
Model systemHuman (paediatric retrospective cohort)
JournalBritish Journal of Haematology
Year2026
Peer reviewedYes
Record last updated2026-08-22
SourceDOI 10.1111/bjh.70795

Extracted findings

InterventionSirolimus
TargetmTOR
ModelHuman
EffectReported effective for paediatric Evans syndrome and secondary autoimmune cytopenias

Cite this paper

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McNeill, M., et al. (2026). Sirolimus is effective for paediatric Evans syndrome and secondary autoimmune cytopenias: A retrospective cohort study. British Journal of Haematology. https://doi.org/10.1111/bjh.70795

@article{MCNEILL2026,
  author       = {McNeill, M. and Cellarius, C. and Illamperuma, N. and others},
  title        = {{Sirolimus is effective for paediatric Evans syndrome and secondary autoimmune cytopenias: A retrospective cohort study}},
  journal      = {British Journal of Haematology},
  year         = {2026},
  doi          = {10.1111/bjh.70795},
}

Cite this Atlas record

The record is the Atlas's own work — the evidence label, the extracted findings and the links. It is cited as part of the dataset, not as the paper.

Barton, O. (2026). Oliver's mTOR Atlas (record MCNEILL2026) [Data set]. https://mtor-atlas.org/study/MCNEILL2026/ · Dataset DOI 10.5281/zenodo.22059963

@misc{atlas_MCNEILL2026,
  author       = {Barton, Oliver},
  title        = {{Oliver's mTOR Atlas}, record MCNEILL2026},
  howpublished = {Data set},
  year         = {2026},
  url          = {https://mtor-atlas.org/study/MCNEILL2026/},
  doi          = {10.5281/zenodo.22059963}
}