Sen Zhang
Contributed to a study showing that largemouth bass have a weak insulin/mTOR/SREBP1 fat-making pathway, so excess dietary carbohydrate is stored as liver glycogen rather than fat
Fish nutrition & physiology researcher · Shanghai Ocean University, China
Sen Zhang is based at Shanghai Ocean University's Research Centre of Environmental Ecology and Fish Nutrition. In a 2026 FASEB Journal paper, the team compared largemouth bass (which handles dietary carbohydrate poorly) with Nile tilapia, showing that high-carbohydrate diets fail to properly engage the insulin-responsive AKT1/mTOR/SREBP1 lipogenesis pathway in bass liver, so surplus glucose piles up as glycogen instead of being converted to fat.
Milestones in the Atlas
| Year | Evidence | Study |
|---|---|---|
| 2026 | A | Impaired mTOR/SREBP1-Mediated Lipogenesis as a Mechanism of Hepatic Glycogen Accumulation in a Carnivorous Fish Model, Largemouth Bass (Micropterus salmoides) TAO2026 Co-author on the largemouth bass study showing impaired mTOR/SREBP1 lipogenesis redirects excess carbohydrate into hepatic glycogen. |
Co-authors in the Atlas
People with a profile here who share at least one study with Sen Zhang.
- Jiaxiong He Contributing co-author in Songlin Li's aquaculture-nutrition team studying mTOR/SREBP1-driven lipogenesis in fish.
- Shiwen Chen Aquaculture physiologist studying why the largemouth bass, a carnivorous fish, tolerates dietary carbohydrate so poorly