Oliver's mTOR Atlas Evidence Platform
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Sen Zhang

Contributed to a study showing that largemouth bass have a weak insulin/mTOR/SREBP1 fat-making pathway, so excess dietary carbohydrate is stored as liver glycogen rather than fat

Fish nutrition & physiology researcher · Shanghai Ocean University, China

Sen Zhang is based at Shanghai Ocean University's Research Centre of Environmental Ecology and Fish Nutrition. In a 2026 FASEB Journal paper, the team compared largemouth bass (which handles dietary carbohydrate poorly) with Nile tilapia, showing that high-carbohydrate diets fail to properly engage the insulin-responsive AKT1/mTOR/SREBP1 lipogenesis pathway in bass liver, so surplus glucose piles up as glycogen instead of being converted to fat.

Milestones in the Atlas

A selection, not a full bibliography: only papers that meet the Atlas inclusion criteria.

YearEvidenceStudy
2026 A Impaired mTOR/SREBP1-Mediated Lipogenesis as a Mechanism of Hepatic Glycogen Accumulation in a Carnivorous Fish Model, Largemouth Bass (Micropterus salmoides) TAO2026 Co-author on the largemouth bass study showing impaired mTOR/SREBP1 lipogenesis redirects excess carbohydrate into hepatic glycogen.

Co-authors in the Atlas 4

People with a profile here who share at least one study with Sen Zhang.

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  • Jiajie Tao Fish nutrition researcher at Shanghai Ocean University who studies why carnivorous farmed fish such as largemouth bass handle dietary carbohydrate poorly and how this links to mTOR signalling in the liver
  • Jiaxiong He Contributing co-author in Songlin Li's aquaculture-nutrition team studying mTOR/SREBP1-driven lipogenesis in fish.
  • Shiwen Chen Aquaculture physiologist studying why the largemouth bass, a carnivorous fish, tolerates dietary carbohydrate so poorly
  • Songlin Li Fish nutrition scientist at Shanghai Ocean University who leads research on how largemouth bass and other farmed fish use carbohydrate and other nutrients in their feed

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