Ruizhao Wang
Built FPTT, fluorescent 'ticker tapes' that record several signalling pathways in living cells over days, and used its mTOR version to follow mTOR activity oscillating through the cell cycle
PhD (2025), School of Life Sciences, Westlake University · Piatkevich Lab (graduate student 2021–2025) · College of Life Sciences, Zhejiang University
Piatkevich Lab, Westlake University (Hangzhou, Zhejiang, China) ↗ Bluesky@ruizhao.bsky.social ↗ ORCID0000-0003-1608-2322 ↗
Portrait: Piatkevich Lab, Westlake University
Ruizhao Wang completed a PhD in 2025 in Kiryl Piatkevich's lab at Westlake University, in a joint program with Zhejiang University, building fluorescent-protein tools that record how signalling pathways change over time inside living cells. As first author of WANG2026C, Wang designed the fluorescent protein ticker tape (FPTT): multispectral fluorescent proteins fused to self-assembling protein fibres, so that a cell's promoter activity is written onto a growing fibre as a colour-coded timeline. The system logged cFos activity in hippocampal neurons at 3-hour resolution over 8 days, and the team built versions for several pathways, including one for mTOR that showed mTOR activity oscillating with the cell cycle, a pattern also reported in JOS2024 with a different method.
Milestones in the Atlas
A selection, not a full bibliography: only papers that meet the Atlas inclusion criteria.
| Year | Evidence | Study |
|---|---|---|
| 2026 | M | Fluorescent protein ticker tape (FPTT): Multiplexed recording of transcriptional dynamics in living cells and in vivo WANG2026C First author: built the FPTT recording platform, including an mTOR recorder that tracked mTOR activity oscillating through the cell cycle. |
Co-authors in the Atlas 2
People with a profile here who share at least one study with Ruizhao Wang.
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- Jian Jiang Co-developed FPTT, fluorescent 'ticker tapes' that record several signalling pathways in living cells over days, including an mTOR recorder that tracked mTOR activity oscillating through the cell cycle
- Kiryl D. Piatkevich Protein engineer who designs fluorescent proteins and biosensors for imaging cells and brains, trained with Vladislav Verkhusha and Edward Boyden, now running a lab at Westlake University
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