Linling He
Researcher in the Fudan team studying amino-acid sensing and stress resilience in T cells
Researcher · Institute of Metabolism and Integrative Biology, Fudan University, Shanghai
Linling He is affiliated with Fudan University's Institute of Metabolism and Integrative Biology, part of the team led by Xingrong Du and Tong-Jin Zhao. Linling He is a contributing co-author on the 2026 PNAS paper showing that CORVET/HOPS tethering complexes sustain amino-acid levels in activated T cells, licensing mTORC1 signaling for T-cell effector function.
Milestones in the Atlas
A selection, not a full bibliography: only papers that meet the Atlas inclusion criteria.
| Year | Evidence | Study |
|---|---|---|
| 2026 | M | Amino acid homeostasis by CORVET/HOPS: A metabolic and stress resilience checkpoint for T cells WANG2026 Contributing co-author (Fudan IMIB team) on the paper identifying CORVET/HOPS as an amino-acid checkpoint that couples nutrient uptake to mTORC1 activity and stress resilience in T cells. |
Co-authors in the Atlas 2
People with a profile here who share at least one study with Linling He.
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- Jing Wang Showed as first author that the CORVET/HOPS trafficking machinery is needed for T cells to sense amino acids and activate mTORC1
- Xingrong Du Studies how cellular metabolism and signaling shape the function of T cells, regulatory T cells and dendritic cells in tumor immunity, autoimmunity and immunodeficiency.
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