Jiayun He
Contributing co-author in Lei Luo's team studying redox-driven mTOR-eIF4A translational control.
Researcher · College of Pharmaceutical Sciences, Southwest University, Chongqing
Jiayun He is affiliated with Southwest University's College of Pharmaceutical Sciences. The 2026 paper she co-authored (corresponding author Lei Luo) shows that low-dose glucosamine triggers a transient oxidative signal that activates PI3K-AKT-mTORC1 signaling, boosting eIF4A-dependent translation of the drug-efflux pump P-glycoprotein — linked to protection against paraquat lung poisoning in mice.
Milestones in the Atlas
| Year | Evidence | Study |
|---|---|---|
| 2026 | M | Redox-sensitive mTOR-eIF4A signaling promotes selective P-glycoprotein translation. JIN2026 Contributing co-author on the Southwest University study showing redox-activated mTORC1-eIF4A signaling selectively increases P-glycoprotein translation and pulmonary detoxification in paraquat poisoning. |