Oliver's mTOR Atlas Evidence Platform
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Chandrayee Banerjee

Pharmacology researcher at ISF College of Pharmacy in Punjab who writes reviews on signalling pathways and repurposed drugs for multiple sclerosis and other brain diseases

Division of Neuroscience, Department of Pharmacology, ISF College of Pharmacy, affiliated to IK Gujral Punjab Technical University (2026, at the time of the study)

Multiple sclerosis (MS) is a disease in which the immune system attacks myelin, the fatty insulation around nerve fibres in the brain and spinal cord. Chandrayee Banerjee is first author of a 2026 review on how two signalling systems talk to each other in MS (BANERJEE2026). One is the PI3K/Akt/mTOR pathway, which controls growth and metabolism in immune cells and in the oligodendrocytes that make myelin. The other is JAK/STAT, which carries signals from inflammatory messengers into the cell nucleus. The review argues that the two pathways reinforce each other in driving Th17 inflammatory T cells and microglia, the brain's immune cells, and that mTOR has two faces in MS: it helps oligodendrocytes mature and rebuild myelin, but too much of it feeds damage. It is a review of earlier studies, not new experiments, and drugs that hit both pathways at once have not been tested in people with MS.

PubMed lists three 2026 papers with Banerjee, all from Sidharth Mehan's neuroscience group in the Department of Pharmacology at ISF College of Pharmacy in Moga. The other two are reviews on repurposing older drugs for brain disease: the antihistamine clemastine as a promoter of myelin repair, and the osteoporosis drug raloxifene as a possible neuroprotective agent. No institutional profile page was found, so the position shown is the one on these papers.

Milestones in the Atlas

A selection, not a full bibliography: only papers that meet the Atlas inclusion criteria.

YearEvidenceStudy
2026 R Decoding the PI3K/Akt/mTOR-JAK/STAT signaling axis in multiple sclerosis: mechanistic crosstalk and therapeutic opportunities. BANERJEE2026 First author of the review mapping crosstalk between PI3K/Akt/mTOR and JAK/STAT signalling in multiple sclerosis.

Co-authors in the Atlas 1

People with a profile here who share at least one study with Chandrayee Banerjee.

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  • Manoj Tongra Chief Scientific Officer of Celagenex Research in Mumbai, senior author of reviews and animal studies that link the PI3K/Akt/mTOR pathway to brain and immune disorders

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