Pathway link TBC1D7-TSC
TBC1D7 TSC1/TSC2
TBC1D7 required-for TSC1/TSC2.
TBC1D7 is a smaller, easy-to-miss third piece of the TSC brake; losing it weakens the brake without removing it.
The conditions it holds under
One study in human cells (DIB2012). A single study; consequences beyond cell-level complex assembly are not tested in whole animals or in people.
- Time it takes
- always on
- Step
- direct (one molecule acts on the other)
- Measured in
- human cells
- Where in the cell
- cytosol
- Reaches people?
- plausible in people, not shown directly
- How settled
- settled in the literature
Studies behind it
| Year | Evidence | Study |
|---|---|---|
| 2012 | M | TBC1D7 is a third subunit of the TSC1-TSC2 complex upstream of mTORC1DIB2012 TBC1D7 is the third core subunit of the TSC1-TSC2 complex regulating Rheb/mTORC1. |
Points the other way
No study in the Atlas contradicts this link. That means none in this curated set, not none in the literature.
Who has checked this
- Checked by
- No researcher outside the project has checked this link yet.
- Curator sign-off
- Not signed off yet. This link was drafted with AI help and has not been reviewed link by link; treat it as a proposal until it is.
- Curated by
- Oliver Barton, with AI help for drafting; see how links are checked.
← The whole pathway · This link as JSON
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