Oliver's mTOR Atlas Evidence Platform
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Pathway link TBC1D7-TSC

TBC1D7 TSC1/TSC2

TBC1D7 required-for TSC1/TSC2.

TBC1D7 is a smaller, easy-to-miss third piece of the TSC brake; losing it weakens the brake without removing it.

TBC1D7 is the third, often-forgotten subunit of the TSC complex; losing it weakens the brake without removing it.

The conditions it holds under

One study in human cells (DIB2012). A single study; consequences beyond cell-level complex assembly are not tested in whole animals or in people.

Time it takes
always on
Step
direct (one molecule acts on the other)
Measured in
human cells
Where in the cell
cytosol
Reaches people?
plausible in people, not shown directly
How settled
settled in the literature

Studies behind it

YearEvidenceStudy
2012 M TBC1D7 is a third subunit of the TSC1-TSC2 complex upstream of mTORC1DIB2012 TBC1D7 is the third core subunit of the TSC1-TSC2 complex regulating Rheb/mTORC1.

Points the other way

No study in the Atlas contradicts this link. That means none in this curated set, not none in the literature.

Who has checked this

Checked by
No researcher outside the project has checked this link yet.
Curator sign-off
Not signed off yet. This link was drafted with AI help and has not been reviewed link by link; treat it as a proposal until it is.
Curated by
Oliver Barton, with AI help for drafting; see how links are checked.

“How settled” describes how far researchers in the field agree. It is not the same as the sign-off above, which only says whether a named curator has checked this page.

If this link rests on your own work: a click on “This looks right” below, or a short note through “Report an error”, helps us more than anything else on this page.

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