Yulian Xiao
Contributed to a study identifying a tRNA fragment (tRF-17-8SPOL52) that drives bortezomib resistance in multiple myeloma by activating autophagy
Hematology researcher · Third Xiangya Hospital, Central South University, China
Yulian Xiao is affiliated with the Department of Hematology at the Third Xiangya Hospital of Central South University. She is a co-author, alongside lead author Fu Yunfeng, of work showing that the tRNA-derived fragment tRF-17-8SPOL52 suppresses the autophagy inhibitor RUBCN, boosts autophagic flux, and thereby helps multiple myeloma cells resist the proteasome inhibitor bortezomib.
Milestones in the Atlas
| Year | Evidence | Study |
|---|---|---|
| 2026 | M | tRNA-derived fragment tRF-17-8SPOL52 induces resistance to bortezomib in multiple myeloma via autophagy activation. FU2026 Co-author on the myeloma study identifying the tRNA fragment tRF-17-8SPOL52 as an autophagy-driven mechanism of bortezomib resistance. |