Vincent Ollendorff
Co-led the Montpellier team that built AIMTOR, a light-emitting biosensor for watching mTOR activity inside living cells, as part of his work on muscle metabolism
Director (since 2022), DMEM (Dynamique Musculaire et Métabolisme), INRAE · Université de Montpellier
DMEM (Dynamique Musculaire et Métabolisme), INRAE · Université de Montpellier (Montpellier, France) ↗ ORCID0000-0001-9751-2202 ↗
Portrait: ResearchGate
Vincent Ollendorff studies how muscle cells manage their metabolism, at the DMEM unit run jointly by INRAE and the University of Montpellier. Muscle differentiation — the process by which young muscle precursor cells fuse and mature into working muscle fibers — is tightly controlled by nutrient-sensing pathways including mTOR.
As a corresponding author on the AIMTOR biosensor study, he co-led the effort to turn that biosensor into a working tool and to use it to track mTORC1 activity as muscle cells differentiate and respond to amino acids like leucine — giving a live readout of a signaling pathway that used to be measurable only after the fact.
Milestones in the Atlas
| Year | Evidence | Study |
|---|---|---|
| 2020 | M | AIMTOR, a BRET biosensor for live imaging, reveals subcellular mTOR signaling and dysfunctions BOU2020 Co-led development of the AIMTOR biosensor and its use to track mTORC1 activity live as muscle cells differentiate and respond to amino-acid stimulation. |
Co-authors in the Atlas
People with a profile here who share at least one study with Vincent Ollendorff.
- Julie Perroy Neurobiologist who co-led AIMTOR, a biosensor for watching mTOR activity live in single cells and in separate parts of the cell
- Nathalie Bouquier Built AIMTOR, a glowing biosensor that lets researchers watch mTOR activity move around inside a living cell in real time