Simran Motwani
First author of the 2026 Nature Communications study on RICTOR, vitamin B12 diets and longevity in C. elegans.
National Institute of Immunology, Delhi
Simran Motwani is first author of MOT2026. In the worm C. elegans, loss of the mTORC2 component RICTOR extended lifespan and stress tolerance, but only on vitamin B12-rich bacterial diets with optimal methionine. The benefit needed two B12-dependent enzymes and a rise in succinate that fragments mitochondria and switches on mitophagy.
In PubMed Simran Motwani is listed at the Molecular Aging Laboratory of the National Institute of Immunology in Delhi.
Milestones in the Atlas
A selection, not a full bibliography: only papers that meet the Atlas inclusion criteria.
| Year | Evidence | Study |
|---|---|---|
| 2026 | A | RICTOR regulates an interspecies crosstalk that influences longevity through a methionine cycle-mitophagy axis MOT2026 First author. In worms, loss of RICTOR extends lifespan on B12-rich diets through a methionine cycle and mitophagy axis. |
Co-authors in the Atlas 1
People with a profile here who share at least one study with Simran Motwani.
ShowHide
- Arnab Mukhopadhyay Studies how diet and gene activity interact to set lifespan in the roundworm C. elegans; his 2026 paper links loss of the mTORC2 component RICTOR to longevity on vitamin B12-rich diets through the methionine cycle and mitophagy.
Every researcher with a profile →
Thank you. That helps us know which pages have been read by someone who knows the work.
Thank you. We will check it and correct the page.
Thank you. Your answer was counted anonymously.