Shohei Hori
Senior author; laboratory head studying regulatory T cell differentiation and immune tolerance
Professor, Laboratory of Immunology and Microbiology, Graduate School of Pharmaceutical Sciences, The University of Tokyo
Shohei Hori leads the Laboratory of Immunology and Microbiology at the University of Tokyo's Graduate School of Pharmaceutical Sciences, having previously headed the Laboratory for Immune Homeostasis at RIKEN's Center for Integrative Medical Sciences.
Senior author of a 2026 PNAS study defining how mTORC1 activity downstream of the T-cell receptor epigenetically stabilizes the master Treg transcription factor Foxp3 through enhanced translation of TET DNA-demethylation enzymes.
Milestones in the Atlas
| Year | Evidence | Study |
|---|---|---|
| 2026 | M | TCR-mTORC1 signaling promotes epigenetic stabilization of Foxp3 expression in regulatory T cells via TET protein translation KIN2026 Senior author: mTORC1 downstream of TCR signaling epigenetically stabilizes Foxp3 in regulatory T cells via TET protein translation. |
Co-authors in the Atlas
People with a profile here who share at least one study with Shohei Hori.
- Tomohide Kinoshita First author identifying how TCR-driven mTORC1 signaling epigenetically locks in Foxp3 expression in regulatory T cells