Peng Cao
Wound-repair researcher at the Burn and Trauma Treatment Center in Wuxi who tests natural compounds against scarring and diabetic wound inflammation
Burn and Trauma Treatment Center, Affiliated Hospital of Jiangnan University, and Wuxi School of Medicine, Jiangnan University (2026)
Hypertrophic scars are thick, raised scars that form after burns or surgery when skin cells called fibroblasts lay down too much collagen. In a 2026 study in Frontiers in Pharmacology, Peng Cao and colleagues tested dihydromyricetin, a plant compound, on fibroblasts taken from such scars and on scars in the rabbit ear, a standard animal model. The compound lowered collagen I and III and the scar marker alpha-smooth muscle actin, and the rabbit scars became flatter. At the same time the activating chemical tags on AKT and mTOR, two growth-signalling proteins, fell. The authors state that this does not prove the compound works through the mTOR pathway.
Cao works at the Burn and Trauma Treatment Center of the Affiliated Hospital of Jiangnan University and at Jiangnan University's Wuxi School of Medicine, in a group led by Guozhong Lyu that also belongs to a Ministry of Education engineering research centre for wound repair technology. In another 2026 first-author paper Cao studied alpha-mangostin, a compound from the mangosteen fruit, and found in cultured mouse immune cells that it reduced inflammation and oxidative stress caused by high glucose, a model of diabetic wounds. Earlier career details could not be confirmed.
Milestones in the Atlas
A selection, not a full bibliography: only papers that meet the Atlas inclusion criteria.
| Year | Evidence | Study |
|---|---|---|
| 2026 | A | Dihydromyricetin attenuates fibrosis-associated features of hypertrophic scar with accompanying changes in PI3K/AKT/mTOR-related signaling. CAO2026B First author: dihydromyricetin reduced scar markers in fibroblasts and rabbit ear scars, with lower AKT and mTOR phosphorylation. |
Co-authors in the Atlas 2
People with a profile here who share at least one study with Peng Cao.
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- Guozhong Lyu Burn and wound-repair specialist in Wuxi whose group studies natural compounds, biomaterials and devices that improve healing and reduce scarring
- Yunwei Wang Burn and wound-repair researcher who contributed to a study testing the plant flavonoid dihydromyricetin as an anti-scarring treatment
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