Meijie Li
Dartmouth researcher, working with the Luikart and Hong labs, studying how PTEN controls the neuronal microtubule cytoskeleton through mTORC2 rather than mTORC1
Department of Molecular and Systems Biology · Geisel School of Medicine at Dartmouth College · Hanover, NH, USA
Meijie Li works at Dartmouth's Geisel School of Medicine with Bryan Luikart (now at the University of Alabama at Birmingham) and Jennifer Hong studying how the tumor-suppressor PTEN shapes neuronal growth. The study behind this entry showed that PTEN loss accelerates microtubule polymerization in peripheral sensory neurons specifically via mTORC2 — not mTORC1 — and only at the axon's growth cone, pointing to the growth-cone microtubule cytoskeleton as a potential target for nerve-regeneration therapies.
PubMed shows Li as a co-author on an earlier (2022) paper from the same group on PTEN and dendritic arborization via microtubule polymerization, indicating a multi-year role in this research line.
Milestones in the Atlas
A selection, not a full bibliography: only papers that meet the Atlas inclusion criteria.
| Year | Evidence | Study |
|---|---|---|
| 2026 | M | PTEN regulates microtubule polymerization via mTORC2, but not mTORC1, in peripheral sensory neurons EVA2026 Co-author on the Dartmouth study showing that PTEN loss accelerates microtubule polymerization in peripheral sensory neuron growth cones through mTORC2, not mTORC1. |
Co-authors in the Atlas 2
People with a profile here who share at least one study with Meijie Li.
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- Jennifer Hong Neurosurgeon-scientist who studies peripheral nerve regeneration and epilepsy
- Simone Evans Neuroscience researcher at Dartmouth who studies how growth signals shape the skeleton of sensory nerve fibres, and first author of work showing that PTEN acts on microtubules through mTORC2 rather than mTORC1
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