Jennifer Hong
Neurosurgeon-scientist who studies peripheral nerve regeneration and epilepsy
Associate Professor of Surgery and of Molecular and Systems Biology · Geisel School of Medicine at Dartmouth
Portrait: Dartmouth Health
Jennifer Hong is Associate Professor of Surgery and of Molecular and Systems Biology at the Geisel School of Medicine at Dartmouth. She is a practising stereotactic and functional neurosurgeon and runs a translational research programme on peripheral nerve regeneration and epilepsy.
In the Atlas she is senior author of EVA2026. In mouse sensory neurons lacking PTEN, the team deleted either raptor (to block mTORC1) or rictor (to block mTORC2). Only blocking mTORC2 brought the faster microtubule growth back to normal, so the signal from PTEN loss to the cytoskeleton runs through mTORC2, not mTORC1.
Milestones in the Atlas
A selection, not a full bibliography: only papers that meet the Atlas inclusion criteria.
| Year | Evidence | Study |
|---|---|---|
| 2026 | M | PTEN regulates microtubule polymerization via mTORC2, but not mTORC1, in peripheral sensory neurons EVA2026 Senior author: in PTEN-null sensory neurons, mTORC2 rather than mTORC1 drives faster microtubule polymerisation (mouse neurons). |
Co-authors in the Atlas 2
People with a profile here who share at least one study with Jennifer Hong.
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- Meijie Li Dartmouth researcher, working with the Luikart and Hong labs, studying how PTEN controls the neuronal microtubule cytoskeleton through mTORC2 rather than mTORC1
- Simone Evans Neuroscience researcher at Dartmouth who studies how growth signals shape the skeleton of sensory nerve fibres, and first author of work showing that PTEN acts on microtubules through mTORC2 rather than mTORC1
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