Jiaqi Zhao
Co-author; chemical biologist who helped build a chemical probe revealing a glycolytic enzyme's secret second job as a methionine sensor for mTORC1.
Chemical biology researcher · Southern University of Science and Technology (SUSTech), Shenzhen
To find the cell's methionine sensor directly, Zhao and colleagues built a 'Trojan horse' chemical probe: a photoaffinity version of methionine that tags whatever protein grabs onto it when hit with light. That fishing expedition landed on PKM2 — an enzyme best known for its day job in glucose metabolism — which the team showed binds methionine through a newly identified pocket and relays that signal through GATOR2 to control mTORC1.
Milestones in the Atlas
A selection, not a full bibliography: only papers that meet the Atlas inclusion criteria.
| Year | Evidence | Study |
|---|---|---|
| 2026 | M | "Trojan" Methionine Probe Reveals PKM2 as a Methionine-Sensing Protein in the mTORC1 Pathway SANG2026 Co-author on a chemical-biology study using a photoaffinity methionine probe to identify PKM2 as a direct methionine-sensing protein that signals through the GATOR2 complex to regulate mTORC1. |
Co-authors in the Atlas 2
People with a profile here who share at least one study with Jiaqi Zhao.
ShowHide
- Jie Wang Corresponding author of a 2026 JACS paper identifying PKM2 as a direct methionine-sensing protein that signals into mTORC1 via GATOR2.
- Zixin Sang Chemical biologist at SUSTech in Shenzhen who used a light-activated methionine probe to identify PKM2 as a methionine sensor for mTORC1
Every researcher with a profile →
Thank you. That helps us know which pages have been read by someone who knows the work.
Thank you. We will check it and correct the page.
Thank you. Your answer was counted anonymously.