Ioannis P. Androulakis
Models how circadian rhythm and nutrient-sensing pathways like mTORC1 stay synchronized
Professor, Biomedical Engineering & Chemical and Biochemical Engineering, Rutgers University · adjunct, Department of Surgery, Robert Wood Johnson Medical School · PhD, Chemical Engineering, Purdue University (1993)
Androulakis Group, Rutgers (Piscataway, New Jersey, USA) ↗ ORCID0000-0002-3795-3628 ↗
Portrait: Rutgers University, Dept. of Biomedical Engineering
Ioannis Androulakis runs a systems-biology and -pharmacology group at Rutgers focused on the interactions between circadian rhythms, inflammation and metabolism. In LU2026, his group built a mathematical model of the liver's peripheral clock in which mTORC1 and GCN2-ISR signalling jointly determine how well the clock stays synchronized to feeding rhythms under nutrient stress — a computational companion to the experimental case, elsewhere in this Atlas, that mTORC1's pattern over time, not just its average level, is what matters.
Milestones in the Atlas
A selection, not a full bibliography: only papers that meet the Atlas inclusion criteria.
| Year | Evidence | Study |
|---|---|---|
| 2026 | M | Mathematical Modeling of Dietary Timing- and Protein Quality-Responsive Liver Circadian Clock and its Function on Ribosome Biogenesis LU2026 Senior author on a model in which liver mTORC1 and GCN2-ISR signalling jointly set circadian entrainability, predicting individualized recovery trajectories after a disrupted feeding schedule. |
Co-authors in the Atlas 1
People with a profile here who share at least one study with Ioannis P. Androulakis.
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- Lingjun Lu Built a computational model treating mTORC1 as a rhythm set by meal timing, not a fixed level
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