Ingrid Grummt
Last author of the 2004 Genes & Development study showing that mTOR activates TIF-IA to link rRNA synthesis to nutrients.
German Cancer Research Center (DKFZ), Heidelberg
Ingrid Grummt is last author of MAY2004, which placed mTOR on the RNA polymerase I branch of ribosome building: rapamycin inactivates the transcription factor TIF-IA, which stops ribosomal RNA synthesis when nutrients or growth factors are missing. The paper lists the Division of Molecular Biology of the Cell II at the German Cancer Research Center in Heidelberg.
Milestones in the Atlas
A selection, not a full bibliography: only papers that meet the Atlas inclusion criteria.
| Year | Evidence | Study |
|---|---|---|
| 2004 | M | mTOR-dependent activation of the transcription factor TIF-IA links rRNA synthesis to nutrient availability MAY2004 Last author. mTOR-dependent phosphorylation of TIF-IA couples rRNA synthesis to nutrient availability. |
Co-authors in the Atlas 1
People with a profile here who share at least one study with Ingrid Grummt.
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- Christine Mayer First author of the 2004 Genes & Development study showing that mTOR activates TIF-IA to link rRNA synthesis to nutrients.
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