Giancarlo Maruri Munaretto
Member of the Department of Medicine at Universidade do Contestado in Santa Catarina, Brazil, and senior author of a 2026 meta-analysis of everolimus after heart transplantation
Department of Medicine, Universidade do Contestado, Concórdia, Santa Catarina (papers 2026; at the time of the study)
After a heart transplant, patients take drugs for life to stop the immune system from attacking the new heart. The standard drugs, calcineurin inhibitors such as tacrolimus, can damage the kidneys, and over the years many transplanted hearts develop cardiac allograft vasculopathy, a thickening of the coronary arteries. Everolimus blocks mTOR, which slows the growth of immune cells and of the cells in artery walls. Giancarlo Maruri Munaretto was senior author of a 2026 meta-analysis in JHLT Open (VITTE2026) that pooled 60 studies with 1,786 heart transplant recipients to weigh up everolimus.
A meta-analysis combines the results of many separate studies to get a clearer overall answer. Here, everolimus-based treatment slowed the artery thickening seen on intravascular ultrasound and kept kidney function better when the dose of calcineurin inhibitors was lowered. Deaths were about the same, but side effects and stopping the drug were more common. The study draws on data from people, so it speaks directly to patient care.
PubMed lists Munaretto at the Department of Medicine of Universidade do Contestado in Concordia, Santa Catarina, Brazil, as senior author of one other 2026 meta-analysis, on sealing the needle track with saline to prevent a collapsed lung after CT-guided lung biopsy. No personal page was found to show career stage.
Milestones in the Atlas
A selection, not a full bibliography: only papers that meet the Atlas inclusion criteria.
| Year | Evidence | Study |
|---|---|---|
| 2026 | S | Efficacy and safety of everolimus in heart transplant recipients: A meta-analysis VITTE2026 Senior author of the meta-analysis showing that everolimus slows cardiac allograft vasculopathy and protects kidney function after heart transplantation, with more side effects. |
Co-authors in the Atlas 1
People with a profile here who share at least one study with Giancarlo Maruri Munaretto.
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- Sofia Helena Vitte Brazilian medical researcher who works on evidence synthesis and cardiometabolic studies, and first author of the 2026 meta-analysis of everolimus in heart transplant recipients
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