Andreas Milias-Argeitis
Follows TORC1 activity through the cell cycle in single yeast cells and builds light-controlled tools to perturb it
Associate Professor, Molecular Systems Biology, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen · PhD, Automatic Control Laboratory, ETH Zurich (2013)
Milias-Argeitis Lab, Molecular Systems Biology, University of Groningen (Groningen, Netherlands) ↗ ORCID0000-0002-4291-4228 ↗
Portrait: University of Groningen
Andreas Milias-Argeitis came to biology from engineering. He studied electrical engineering at the University of Patras, earned his PhD at the Automatic Control Laboratory of ETH Zurich in 2013, and was a postdoc in ETH's Department of Biosystems Science and Engineering before joining the University of Groningen in 2016.
His group films hundreds of single yeast cells to ask how growth signals are coordinated with division. They found that TORC1 and PKA activity towards ribosome biogenesis rises and falls in step with the cell cycle even when conditions outside the cell stay constant. In 2026 they added OPTO-Cln2, a light-controlled switch for G1 progression, to test how that oscillation is tied to the cycle.
Milestones in the Atlas
| Year | Evidence | Study |
|---|---|---|
| 2022 | M | TORC1 and PKA activity towards ribosome biogenesis oscillates in synchrony with the budding yeast cell cycle GUE2022 Senior author: TORC1/PKA output to ribosome biogenesis oscillates with the yeast cell cycle under constant conditions. |