RAFT1 phosphorylation of the translational regulators p70 S6 kinase and 4E-BP1

The complex of rapamycin with its intracellular receptor, FKBP12, interacts with RAFT1/FRAP/mTOR, the in vivo rapamycin-sensitive target and a member of the ataxia telangiectasia mutated (ATM)-related family of kinases that share homology with the catalytic domain of phosphatidylinositol 3-kinase. The function of RAFT1 in the rapamycin-sensitive pathway and its connection to downstream components of the pathway, such as p70 S6 kinase and 4E-BP1, are poorly understood.

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Burnett, P. E., et al. (1998). RAFT1 phosphorylation of the translational regulators p70 S6 kinase and 4E-BP1. Proceedings of the National Academy of Sciences of the United States of America. https://doi.org/10.1073/pnas.95.4.1432

@article{BUR1998,
  author       = {Burnett, P. E. and Sabatini, D. M. and others},
  title        = {{RAFT1 phosphorylation of the translational regulators p70 S6 kinase and 4E-BP1}},
  journal      = {Proceedings of the National Academy of Sciences of the United States of America},
  year         = {1998},
  doi          = {10.1073/pnas.95.4.1432},
  note         = {PMID: 9465032},
}

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The record is the Atlas's own work — the evidence label, the extracted findings and the links. It is cited as part of the dataset, not as the paper.

Barton, O. (2026). Oliver's mTOR Atlas (record BUR1998) [Data set]. https://mtor-atlas.org/study/BUR1998/ · Dataset DOI 10.5281/zenodo.22059963

@misc{atlas_BUR1998,
  author       = {Barton, Oliver},
  title        = {{Oliver's mTOR Atlas}, record BUR1998},
  howpublished = {Data set},
  year         = {2026},
  url          = {https://mtor-atlas.org/study/BUR1998/},
  doi          = {10.5281/zenodo.22059963}
}