Yang Yu
Anesthesiologist and researcher at Tianjin Medical University General Hospital who studies hydrogen gas as a treatment for sepsis and its brain damage, and co-senior author of the 2026 study linking hydrogen, mTOR and myelin repair
Department of Anesthesia, Tianjin Medical University General Hospital · Tianjin Institute of Anesthesiology (papers from at least 2020 to 2026)
Sepsis is a body-wide reaction to infection that can damage the brain, leaving survivors with memory problems. In the Atlas study YU2026, led by first author Jiafeng Yu with Yang Yu and Yonghao Yu as corresponding authors, septic mice had overactive mTOR in the medial prefrontal cortex. This kept oligodendrocyte precursor cells from maturing into the cells that make myelin, the insulation around nerve fibres, and the mice lost myelin and memory. Breathing high-concentration hydrogen gas lowered mTOR activity, restored myelin and improved memory; rapamycin had a similar effect. The work was done in mice.
Hydrogen gas is studied as a mild antioxidant and anti-inflammatory treatment. On PubMed, Yang Yu appears with Yonghao Yu in the Department of Anesthesiology at Tianjin Medical University General Hospital on earlier hydrogen studies in septic mice, including a 2020 paper showing that hydrogen protected the gut in severe sepsis through the Nrf2 pathway. Rank and training could not be confirmed.
Milestones in the Atlas
A selection, not a full bibliography: only papers that meet the Atlas inclusion criteria.
| Year | Evidence | Study |
|---|---|---|
| 2026 | A | High-concentration hydrogen mitigates cognitive impairment in a murine model of Sepsis-associated encephalopathy by enhancing oligodendrocyte maturation and myelination in the mPFC YU2026 Co-senior (last) author: co-led the mouse study showing that hydrogen gas restores myelin and memory after sepsis by restraining mTOR in the prefrontal cortex. |
Co-authors in the Atlas 1
People with a profile here who share at least one study with Yang Yu.
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- Jiafeng Yu Anesthesiology researcher at Tianjin Medical University General Hospital and first author of a mouse study showing that breathing hydrogen gas protects memory after sepsis by calming mTOR in brain support cells
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