Sen Hong
First-authored the cryo-EM structure identifying TM6SF1 as a lysosomal cholesterol-binding protein involved in regulating mTORC1 signalling
Hobbs Lab & Li (Xiaochun) Lab, University of Texas Southwestern Medical Center
Portrait: Sen Hong / UT Southwestern
Sen Hong is a structural biologist working across the Hobbs and Li labs at UT Southwestern, applying cryo-electron microscopy to membrane proteins involved in lipid and cholesterol biology.
Milestones in the Atlas
| Year | Evidence | Study |
|---|---|---|
| 2026 | M | Structure and function of TM6SF1 reveals role in mTORC1 signaling HON2026 First-authored the cryo-EM structure of TM6SF1, showing the protein binds cholesterol and directly engages LAMTOR1 to regulate mTORC1 signaling. |
Co-authors in the Atlas
People with a profile here who share at least one study with Sen Hong.
- Xiaochun Li Solves cryo-EM structures of cholesterol-sensing membrane proteins, including the new mTORC1 regulator TM6SF1