Juan Yang
Contributed to a study showing that the Brucella suis vaccine strain S2 drives macrophage polarisation and autophagy through PI3K/Akt/mTOR signalling to survive inside cells
Neurology researcher · General Hospital of Ningxia Medical University, China
Juan Yang works in the Department of Neurology at the General Hospital of Ningxia Medical University. She is a co-author of a 2026 study using BV2 macrophage cells to dissect how the live vaccine strain Brucella suis S2 manipulates host macrophage polarization and autophagy through the PI3K/Akt/mTOR axis to prolong its own intracellular survival — a mechanism relevant to chronic infection and brucellosis relapse.
Milestones in the Atlas
| Year | Evidence | Study |
|---|---|---|
| 2026 | M | Brucella suis vaccine strain 2 promotes intracellular proliferation by inducing M2 macrophage polarization and autophagy through PI3K/Akt/mTOR signalling. LI2026B Co-author on the BV2-macrophage study linking Brucella suis S2's M2 polarization/autophagy strategy to PI3K/Akt/mTOR signalling. |