Beatrix M. Ueberheide
Mass spectrometry and proteomics specialist who directs NYU's proteomics core and contributed the protein profiling to the Down syndrome hippocampus mTOR study.
Associate Professor, Biochemistry and Molecular Pharmacology and Neurology, NYU Grossman School of Medicine · Director, Proteomics Resource Center
Portrait: NYU Grossman School of Medicine
Beatrix Ueberheide is an associate professor at NYU Grossman School of Medicine, in the departments of Biochemistry and Molecular Pharmacology and of Neurology, and director of the Proteomics Resource Center. Her profile lists work on biological mass spectrometry, de novo protein sequencing and the structure of peptide toxins.
Proteomics means measuring many proteins at once. In the 2026 Alzheimer's & Dementia paper in the Atlas, her laboratory is the proteomics group of a team led by neuroscientists at the University of Colorado and NYU. She is a middle author, not the senior author.
The study looked at hippocampal tissue from people with Down syndrome who also had Alzheimer's disease changes, and found disruption in upstream regulators of the mTOR and insulin pathways. The paper describes its observations as preliminary.
Milestones in the Atlas
A selection, not a full bibliography: only papers that meet the Atlas inclusion criteria.
| Year | Evidence | Study |
|---|---|---|
| 2026 | M | Disruption of hippocampal upstream regulators of mTOR and insulin pathways in Down syndrome with Alzheimer's disease neuropathology: Preliminary observations NOR2026 Proteomics co-author of the study reporting disrupted hippocampal upstream regulators of mTOR and insulin signalling in Down syndrome with Alzheimer's neuropathology (preliminary observations). |
Co-authors in the Atlas 2
People with a profile here who share at least one study with Beatrix M. Ueberheide.
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- Abigail Nordbeck Neuroscience researcher and first author of a 2026 spatial study of the human hippocampus in Down syndrome with Alzheimer's disease, which found mTOR and insulin signalling disturbed in specific cell layers
- Ann-Charlotte Granholm Neuroscientist of aging who has studied Down syndrome and the Alzheimer's disease that often comes with it since the 1990s, now a professor at the University of Colorado Anschutz Medical Campus
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