TOR signaling in growth and metabolism

The target of rapamycin (TOR) is a conserved Ser/Thr kinase that regulates cell growth and metabolism in response to environmental cues. Here, highlighting contributions from studies in model organisms, we review mammalian TOR complexes and the signaling branches they mediate. TOR is part of two distinct multiprotein complexes, TOR complex 1 (TORC1), which is sensitive to rapamycin, and TORC2, which is not.

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Wullschleger, S., et al. (2006). TOR signaling in growth and metabolism. Cell. https://doi.org/10.1016/j.cell.2006.01.016

@article{WUL2006,
  author       = {Wullschleger, S. and Hall, M. N. and others},
  title        = {{TOR signaling in growth and metabolism}},
  journal      = {Cell},
  year         = {2006},
  doi          = {10.1016/j.cell.2006.01.016},
  note         = {PMID: 16469695},
}

Cite this Atlas record

The record is the Atlas's own work — the evidence label, the extracted findings and the links. It is cited as part of the dataset, not as the paper.

Barton, O. (2026). Oliver's mTOR Atlas (record WUL2006) [Data set]. https://mtor-atlas.org/study/WUL2006/ · Dataset DOI 10.5281/zenodo.22059963

@misc{atlas_WUL2006,
  author       = {Barton, Oliver},
  title        = {{Oliver's mTOR Atlas}, record WUL2006},
  howpublished = {Data set},
  year         = {2026},
  url          = {https://mtor-atlas.org/study/WUL2006/},
  doi          = {10.5281/zenodo.22059963}
}